3GB5
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FMN A 301 |
| Chain | Residue |
| A | ARG96 |
| A | SER212 |
| A | VAL232 |
| A | THR233 |
| A | THR235 |
| A | LEU273 |
| A | ARG275 |
| A | ACT303 |
| A | HOH415 |
| A | HOH416 |
| A | HOH426 |
| A | ARG97 |
| A | HOH443 |
| A | HOH492 |
| A | SER98 |
| A | ARG100 |
| A | PRO123 |
| A | SER124 |
| A | GLY125 |
| A | HIS127 |
| A | TYR208 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 302 |
| Chain | Residue |
| A | SER103 |
| A | SER104 |
| A | ARG266 |
| A | THR284 |
| A | VAL285 |
| A | HIS286 |
| A | ACT304 |
| A | HOH440 |
| A | HOH457 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 303 |
| Chain | Residue |
| A | ALA126 |
| A | FMN301 |
| A | HOH479 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 304 |
| Chain | Residue |
| A | SER265 |
| A | ARG266 |
| A | ASP267 |
| A | HIS286 |
| A | HIS287 |
| A | PO4302 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19436071","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22238141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GB5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GH8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TNZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TO0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"3GFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TNZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19436071","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22238141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TNZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
