3GAW
Solution structure of Human Complement Factor H in 250 mM NaCl buffer
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001851 | molecular_function | complement component C3b binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0006956 | biological_process | complement activation |
| A | 0006957 | biological_process | complement activation, alternative pathway |
| A | 0008201 | molecular_function | heparin binding |
| A | 0030449 | biological_process | regulation of complement activation |
| A | 0030451 | biological_process | regulation of complement activation, alternative pathway |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0043395 | molecular_function | heparan sulfate proteoglycan binding |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0072562 | cellular_component | blood microparticle |
| A | 0106139 | cellular_component | symbiont cell surface |
| A | 1903659 | biological_process | regulation of complement-dependent cytotoxicity |
| A | 1905370 | cellular_component | serine-type endopeptidase complex |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:19139490 |
| Chain | Residue | Details |
| A | ASN217 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17591618, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:2963625 |
| Chain | Residue | Details |
| A | ASN529 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17591618 |
| Chain | Residue | Details |
| A | ASN718 | |
| A | ASN822 | |
| A | ASN1095 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17591618, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | ASN802 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:17591618, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169 |
| Chain | Residue | Details |
| A | ASN882 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17591618, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | ASN911 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:17591618, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | ASN1029 |
