3GAS
Crystal Structure of Helicobacter pylori Heme Oxygenase Hugz in Complex with Heme
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070967 | molecular_function | coenzyme F420 binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070967 | molecular_function | coenzyme F420 binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0070967 | molecular_function | coenzyme F420 binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0070967 | molecular_function | coenzyme F420 binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0070967 | molecular_function | coenzyme F420 binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0070967 | molecular_function | coenzyme F420 binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE HEM A 1290 |
| Chain | Residue |
| A | LYS23 |
| A | GLY239 |
| A | GLY242 |
| A | ASN243 |
| A | PRO244 |
| A | HIS245 |
| A | HOH319 |
| A | HOH347 |
| A | HOH444 |
| A | AZI1296 |
| A | EDO1312 |
| A | PHE24 |
| B | VAL130 |
| B | SER131 |
| B | ALA134 |
| B | HIS136 |
| B | ILE202 |
| B | MSE205 |
| B | PHE208 |
| B | HOH277 |
| A | ILE162 |
| A | ARG166 |
| A | ARG219 |
| A | VAL221 |
| A | PHE224 |
| A | GLY225 |
| A | TYR237 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE AZI A 1296 |
| Chain | Residue |
| A | VAL221 |
| A | GLY223 |
| A | PHE224 |
| A | GLY225 |
| A | HOH271 |
| A | HEM1290 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 1302 |
| Chain | Residue |
| A | LYS124 |
| A | GLN125 |
| A | TYR126 |
| A | LEU213 |
| A | ASP214 |
| A | PHE215 |
| A | HOH569 |
| A | HOH673 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1308 |
| Chain | Residue |
| A | GLU148 |
| A | ARG168 |
| A | LYS170 |
| A | GLU217 |
| A | GLY218 |
| A | HOH961 |
| B | GLU135 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1312 |
| Chain | Residue |
| A | PHE24 |
| A | ILE55 |
| A | GLU56 |
| A | PHE224 |
| A | HOH275 |
| A | HOH308 |
| A | HEM1290 |
| site_id | AC6 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM B 1293 |
| Chain | Residue |
| A | VAL130 |
| A | SER131 |
| A | ALA134 |
| A | HIS136 |
| A | ILE202 |
| A | MSE205 |
| A | PHE208 |
| B | LYS23 |
| B | PHE24 |
| B | ARG166 |
| B | ARG219 |
| B | VAL221 |
| B | PHE224 |
| B | GLY225 |
| B | TYR237 |
| B | GLY239 |
| B | GLY242 |
| B | ASN243 |
| B | PRO244 |
| B | HIS245 |
| B | HOH266 |
| B | HOH269 |
| B | HOH274 |
| B | HOH279 |
| B | AZI1299 |
| B | EDO1319 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE AZI B 1299 |
| Chain | Residue |
| B | GLY223 |
| B | PHE224 |
| B | GLY225 |
| B | HOH264 |
| B | HEM1293 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 1305 |
| Chain | Residue |
| B | LYS124 |
| B | GLN125 |
| B | TYR126 |
| B | LEU213 |
| B | ASP214 |
| B | PHE215 |
| B | HOH301 |
| B | HOH1281 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1310 |
| Chain | Residue |
| B | GLU148 |
| B | ARG168 |
| B | LYS170 |
| B | GLU217 |
| B | ARG219 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1315 |
| Chain | Residue |
| B | GLY86 |
| B | GLU90 |
| B | LYS222 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1316 |
| Chain | Residue |
| B | ASP39 |
| B | SER40 |
| B | GLN41 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1319 |
| Chain | Residue |
| B | PHE24 |
| B | ILE55 |
| B | GLU56 |
| B | PHE224 |
| B | HOH297 |
| B | HOH767 |
| B | HEM1293 |
| site_id | BC4 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE HEM C 1295 |
| Chain | Residue |
| C | LYS23 |
| C | PHE24 |
| C | ARG166 |
| C | ARG219 |
| C | VAL221 |
| C | PHE224 |
| C | GLY225 |
| C | TYR237 |
| C | GLY239 |
| C | GLY242 |
| C | ASN243 |
| C | PRO244 |
| C | HIS245 |
| C | HOH283 |
| C | HOH287 |
| C | HOH356 |
| C | AZI1301 |
| C | EDO1321 |
| D | VAL130 |
| D | SER131 |
| D | VAL133 |
| D | ALA134 |
| D | HIS136 |
| D | ILE202 |
| D | MSE205 |
| D | PHE208 |
| D | HOH269 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE AZI C 1301 |
| Chain | Residue |
| C | VAL221 |
| C | GLY223 |
| C | PHE224 |
| C | GLY225 |
| C | HOH282 |
| C | HEM1295 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 1307 |
| Chain | Residue |
| C | LYS124 |
| C | GLN125 |
| C | TYR126 |
| C | LEU213 |
| C | ASP214 |
| C | PHE215 |
| C | HOH547 |
| C | HOH1285 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1311 |
| Chain | Residue |
| C | GLU135 |
| D | GLU148 |
| D | ARG168 |
| D | LYS170 |
| D | GLU217 |
| D | ARG219 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 1321 |
| Chain | Residue |
| C | PHE24 |
| C | ILE55 |
| C | GLU56 |
| C | PHE224 |
| C | HOH936 |
| C | HEM1295 |
| D | HOH364 |
| site_id | BC9 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM D 1294 |
| Chain | Residue |
| C | VAL130 |
| C | SER131 |
| C | ALA134 |
| C | HIS136 |
| C | ILE202 |
| C | MSE205 |
| C | PHE208 |
| C | HOH268 |
| D | LYS23 |
| D | PHE24 |
| D | ARG166 |
| D | ARG219 |
| D | VAL221 |
| D | PHE224 |
| D | GLY225 |
| D | TYR237 |
| D | GLY239 |
| D | GLY242 |
| D | ASN243 |
| D | PRO244 |
| D | HIS245 |
| D | HOH283 |
| D | HOH297 |
| D | HOH333 |
| D | AZI1300 |
| D | EDO1320 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE AZI D 1300 |
| Chain | Residue |
| D | GLY223 |
| D | PHE224 |
| D | GLY225 |
| D | HOH271 |
| D | HEM1294 |
| site_id | CC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO D 1306 |
| Chain | Residue |
| D | LYS124 |
| D | GLN125 |
| D | TYR126 |
| D | LEU213 |
| D | ASP214 |
| D | PHE215 |
| D | HOH1283 |
| D | HOH1284 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 1320 |
| Chain | Residue |
| C | HOH270 |
| D | PHE24 |
| D | ILE55 |
| D | GLU56 |
| D | PHE224 |
| D | HEM1294 |
| site_id | CC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 1323 |
| Chain | Residue |
| D | LYS80 |
| D | ASP83 |
| D | GLY86 |
| D | VAL87 |
| D | GLU90 |
| D | LYS222 |
| D | HOH1030 |
| site_id | CC5 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM E 1291 |
| Chain | Residue |
| E | LYS23 |
| E | PHE24 |
| E | ARG166 |
| E | ARG219 |
| E | PHE224 |
| E | GLY225 |
| E | TYR237 |
| E | GLY239 |
| E | GLY242 |
| E | ASN243 |
| E | PRO244 |
| E | HIS245 |
| E | HOH271 |
| E | HOH272 |
| E | HOH297 |
| E | AZI1297 |
| F | VAL130 |
| F | SER131 |
| F | ALA134 |
| F | HIS136 |
| F | ILE202 |
| F | MSE205 |
| F | PHE208 |
| F | HOH291 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE AZI E 1297 |
| Chain | Residue |
| E | GLY223 |
| E | PHE224 |
| E | GLY225 |
| E | HOH263 |
| E | HEM1291 |
| site_id | CC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO E 1303 |
| Chain | Residue |
| E | LYS124 |
| E | GLN125 |
| E | TYR126 |
| E | LEU213 |
| E | ASP214 |
| E | PHE215 |
| E | HOH665 |
| E | HOH1090 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO E 1313 |
| Chain | Residue |
| E | ASP83 |
| E | GLY86 |
| E | VAL87 |
| E | GLU90 |
| E | LYS222 |
| site_id | CC9 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM F 1292 |
| Chain | Residue |
| E | VAL130 |
| E | SER131 |
| E | VAL133 |
| E | ALA134 |
| E | HIS136 |
| E | ILE202 |
| E | MSE205 |
| E | PHE208 |
| E | HOH299 |
| F | LYS23 |
| F | ARG166 |
| F | ARG219 |
| F | VAL221 |
| F | PHE224 |
| F | GLY225 |
| F | TYR237 |
| F | GLY239 |
| F | GLY242 |
| F | ASN243 |
| F | PRO244 |
| F | HIS245 |
| F | HOH273 |
| F | HOH301 |
| F | HOH314 |
| F | AZI1298 |
| F | EDO1318 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE AZI F 1298 |
| Chain | Residue |
| F | VAL221 |
| F | GLY223 |
| F | PHE224 |
| F | GLY225 |
| F | HOH267 |
| F | HEM1292 |
| site_id | DC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO F 1304 |
| Chain | Residue |
| F | LYS124 |
| F | GLN125 |
| F | TYR126 |
| F | LEU213 |
| F | ASP214 |
| F | PHE215 |
| F | HOH293 |
| F | HOH865 |
| site_id | DC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO F 1309 |
| Chain | Residue |
| E | GLU135 |
| F | GLU148 |
| F | ARG168 |
| F | LYS170 |
| F | GLU217 |
| F | GLY218 |
| F | HOH1092 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO F 1314 |
| Chain | Residue |
| B | HOH1175 |
| F | ARG203 |
| F | ALA204 |
| F | HOH368 |
| F | HOH410 |
| site_id | DC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO F 1317 |
| Chain | Residue |
| F | LYS141 |
| F | HIS209 |
| F | HOH1180 |
| site_id | DC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO F 1318 |
| Chain | Residue |
| E | HOH300 |
| F | PHE24 |
| F | ILE55 |
| F | GLU56 |
| F | PHE224 |
| F | HOH1197 |
| F | HEM1292 |
| site_id | DC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO F 1322 |
| Chain | Residue |
| F | GLY86 |
| F | VAL87 |
| F | GLU90 |
| F | LYS222 |
