3GAI

Structure of a F112A variant PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0008817	molecular_function	corrinoid adenosyltransferase activity
A	0009235	biological_process	cobalamin metabolic process
A	0009236	biological_process	cobalamin biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE ATP A 999

Chain	Residue
A	THR5
A	ARG132
A	GLU135
A	ARG136
A	ASN156
A	MG189
A	K190
A	HOH202
A	HOH203
A	HOH206
A	HOH221
A	LYS6
A	B12800
A	ASN7
A	GLY8
A	THR13
A	ARG14
A	LYS23
A	VAL28
A	TYR31

---

site_id	AC2
Number of Residues	27
Details	BINDING SITE FOR RESIDUE B12 A 800

Chain	Residue
A	LYS2
A	ILE3
A	THR5
A	ARG14
A	PHE67
A	GLY70
A	HIS71
A	ALA74
A	LYS111
A	ALA112
A	ILE113
A	ARG128
A	ARG132
A	SER159
A	ASP160
A	PHE163
A	K190
A	CL192
A	HOH197
A	HOH207
A	HOH220
A	HOH222
A	HOH277
A	HOH288
A	HOH313
A	HOH315
A	ATP999

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 189

Chain	Residue
A	ASN156
A	HOH203
A	HOH206
A	ATP999

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K A 190

Chain	Residue
A	ILE3
A	ASP160
A	B12800
A	ATP999

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K A 191

Chain	Residue
A	PRO76
A	ALA77
A	ASP79
A	HIS82
A	HOH260
A	HOH264

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 192

Chain	Residue
A	LYS111
A	ALA112
A	B12800

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 193

Chain	Residue
A	ARG81
A	PRO107
A	ARG167
A	ASP177
A	HOH254

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 888

Chain	Residue
A	GLU61
A	LEU65
A	GLN90
A	TRP94

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 889

Chain	Residue
A	ASN24
A	ALA29
A	ARG136
A	GLN137
A	GLN140
A	HOH250

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 890

Chain	Residue
A	ASP78
A	ASP79
A	GLU80
A	ALA108
A	VAL109
A	LYS110
A	LYS111
A	HOH300

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