Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0008311 | molecular_function | double-stranded DNA 3'-5' DNA exonuclease activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0140078 | molecular_function | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0006281 | biological_process | DNA repair |
| B | 0006284 | biological_process | base-excision repair |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0008311 | molecular_function | double-stranded DNA 3'-5' DNA exonuclease activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0140078 | molecular_function | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 7002 |
| Chain | Residue |
| A | VAL1088 |
| A | ALA1131 |
| A | GLU1134 |
| B | ARG2090 |
| B | HOH9027 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 7004 |
| Chain | Residue |
| A | MET1027 |
| A | GLU1054 |
| A | GLY1055 |
| A | LYS1076 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 7006 |
| Chain | Residue |
| A | LEU1004 |
| A | ILE1033 |
| A | VAL1077 |
| A | PHE1102 |
| A | NA7401 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 7010 |
| Chain | Residue |
| A | LYS1020 |
| A | ASP1242 |
| A | MET1244 |
| A | HOH9105 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 7012 |
| Chain | Residue |
| A | VAL1176 |
| A | ALA1179 |
| A | TRP1180 |
| A | LYS1183 |
| A | HOH9199 |
| A | HOH9219 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 7013 |
| Chain | Residue |
| A | HOH459 |
| A | LYS1183 |
| A | GLU1186 |
| A | ASN1187 |
| B | GLU2054 |
| B | HOH9172 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 7015 |
| Chain | Residue |
| A | PRO1043 |
| A | GLU1044 |
| A | LEU1046 |
| A | ARG1051 |
| B | GLU2228 |
| B | GLU2229 |
| B | HOH9174 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 7020 |
| Chain | Residue |
| A | GLY1055 |
| A | TYR1056 |
| A | ARG1057 |
| A | LYS1076 |
| B | ASP2182 |
| B | GLU2186 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 7024 |
| Chain | Residue |
| A | ASP1103 |
| A | ASP1104 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 7030 |
| Chain | Residue |
| A | ARG1090 |
| A | GLU1120 |
| A | LYS1123 |
| A | TYR1124 |
| A | GLU1127 |
| B | ARG2138 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 7031 |
| Chain | Residue |
| A | HOH443 |
| A | ILE1185 |
| A | TYR1189 |
| A | VAL1190 |
| A | ASP1191 |
| A | ARG1194 |
| A | HOH9268 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 7401 |
| Chain | Residue |
| A | ASP1032 |
| A | THR1075 |
| A | LYS1076 |
| A | VAL1077 |
| A | GOL7006 |
| A | HOH9008 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 7003 |
| Chain | Residue |
| B | GLU2094 |
| B | GLU2120 |
| B | ARG2121 |
| B | HOH9353 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 7011 |
| Chain | Residue |
| A | GLY1087 |
| A | VAL1088 |
| A | GLU1089 |
| B | GLY2087 |
| B | VAL2088 |
| B | GLU2089 |
| B | ASP2092 |
| B | HOH9144 |
| B | HOH9194 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 7021 |
| Chain | Residue |
| B | GLU2158 |
| B | ILE2159 |
| B | LEU2161 |
| B | PRO2164 |
| B | PRO2200 |
| B | HOH9118 |
| B | HOH9167 |
| B | HOH9306 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 7022 |
| Chain | Residue |
| B | ASN2114 |
| B | LYS2116 |
| B | LYS2125 |
| B | ASN2153 |
| B | SER2171 |
| B | GLY2172 |
| B | LEU2221 |
| B | HOH9222 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 7027 |
| Chain | Residue |
| B | PRO2062 |
| B | GLU2084 |
| B | HOH9090 |
| B | HOH9109 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 7032 |
| Chain | Residue |
| B | PRO2175 |
| B | HOH9014 |
| B | SER2168 |
| B | ASN2169 |
| site_id | CC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL B 7033 |
| Chain | Residue |
| B | ASP2191 |
| B | THR2192 |
| B | PHE2193 |
| B | ARG2220 |
| B | ASP2222 |
| B | TYR2223 |
| B | PHE2224 |
| B | TRP2238 |
| B | ILE2239 |
| B | ILE2251 |
| B | HOH9377 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PO4 B 7204 |
| Chain | Residue |
| B | LEU2082 |
| B | ARG2083 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 7205 |
| Chain | Residue |
| B | ASP2104 |
| B | LYS2233 |
| B | ILE2255 |
| B | GLU2256 |
Functional Information from PROSITE/UniProt
| site_id | PS00726 |
| Number of Residues | 10 |
| Details | AP_NUCLEASE_F1_1 AP endonucleases family 1 signature 1. PDILCLQEIK |
| Chain | Residue | Details |
| A | PRO1031-LYS1040 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASN1151 | |
| B | ASN2151 | |
| Chain | Residue | Details |
| A | ASN1012 | |
| A | GLU1038 | |
| B | ASN2012 | |
| B | GLU2038 | |
| Chain | Residue | Details |
| A | ASN1151 | |
| A | ASN1153 | |
| A | HIS1248 | |
| B | ASN2151 | |
| B | ASN2153 | |
| B | HIS2248 | |
