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3G9J

GR DNA binding domain:Pal, 18bp complex-36

Functional Information from GO Data
ChainGOidnamespacecontents
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
A0008270molecular_functionzinc ion binding
A0043565molecular_functionsequence-specific DNA binding
B0003700molecular_functionDNA-binding transcription factor activity
B0006355biological_processregulation of DNA-templated transcription
B0008270molecular_functionzinc ion binding
B0043565molecular_functionsequence-specific DNA binding
Functional Information from PDB Data
site_idAC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO C 19
ChainResidue
CDC16
CDT17

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 1514
ChainResidue
ACYS440
ACYS443
ACYS457
ACYS460

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 1515
ChainResidue
ACYS495
ACYS476
ACYS482
ACYS492

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1
ChainResidue
ALEU475
APRO493
AALA494
BILE487
BASN491

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 1512
ChainResidue
BCYS440
BCYS443
BCYS457
BCYS460

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 1513
ChainResidue
BCYS476
BCYS482
BCYS492
BCYS495

site_idAC7
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 1
ChainResidue
BHOH52
BGLN471
BHIS472
BASN473
BASP481

site_idAC8
Number of Residues8
DetailsBINDING SITE FOR RESIDUE EDO B 526
ChainResidue
BSER459
BVAL462
BPHE463
BARG466
BARG496
CDT12
CDG13
CHOH51

Functional Information from PROSITE/UniProt
site_idPS00031
Number of Residues27
DetailsNUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. ClvCs.Deasgc.HYgvltCgsCkvFFkR
ChainResidueDetails
ACYS440-ARG466

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues130
DetailsDNA_BIND: Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407
ChainResidueDetails
ACYS440-MET505
BCYS440-MET505

site_idSWS_FT_FI2
Number of Residues88
DetailsZN_FING: NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407
ChainResidueDetails
ACYS440-CYS460
ACYS476-CYS500
BCYS440-CYS460
BCYS476-CYS500

site_idSWS_FT_FI3
Number of Residues8
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P04150
ChainResidueDetails
ALYS499
ALYS511
ALYS513
ALYS514
BLYS499
BLYS511
BLYS513
BLYS514

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PDB entries from 2024-11-06

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