3G7E

Crystal structure of E. coli Gyrase B co-complexed with PROP-2-YN-1-YL {[5-(4-PIPERIDIN-1-YL-2-PYRIDIN-3-YL-1,3-THIAZOL-5-YL)-1H-PYRAZOL-3-YL]METHYL}CARBAMATE inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE B46 A 1

Chain	Residue
A	ASN46
A	MET95
A	GLY102
A	PHE104
A	ASP106
A	ARG136
A	HOH406
A	HOH408
A	HOH443
A	ALA47
A	ASP49
A	GLU50
A	ASP73
A	ARG76
A	GLY77
A	ILE78
A	PRO79

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