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3G6M

crystal structure of a chitinase CrChi1 from the nematophagous fungus Clonostachys rosea in complex with a potent inhibitor caffeine

Functional Information from GO Data
ChainGOidnamespacecontents
A0000272biological_processpolysaccharide catabolic process
A0004553molecular_functionhydrolase activity, hydrolyzing O-glycosyl compounds
A0004568molecular_functionchitinase activity
A0005576cellular_componentextracellular region
A0005975biological_processcarbohydrate metabolic process
A0006032biological_processchitin catabolic process
A0008061molecular_functionchitin binding
A0008843molecular_functionendochitinase activity
A0016787molecular_functionhydrolase activity
A0016798molecular_functionhydrolase activity, acting on glycosyl bonds
Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE CFF A 1
ChainResidue
APHE74
AHOH453
ATRP134
AASP172
AGLU174
AMET240
ATYR242
AASP243
ATRP381
ACFF427

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CFF A 427
ChainResidue
ACFF1
ATRP134
AASP243
AHOH901

Functional Information from PROSITE/UniProt
site_idPS00123
Number of Residues9
DetailsALKALINE_PHOSPHATASE Alkaline phosphatase active site. ItDSAAGAT
ChainResidueDetails
AILE336-THR344

site_idPS01095
Number of Residues9
DetailsGH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. FDGIDVDwE
ChainResidueDetails
APHE166-GLU174

248636

PDB entries from 2026-02-04

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