Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3G5A

Crystal Structure of Candida glabrata FMN Adenylyltransferase in complex with FMN and ATP analog AMPCPP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0003919	molecular_function	FMN adenylyltransferase activity
A	0005524	molecular_function	ATP binding
A	0005575	cellular_component	cellular_component
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0006747	biological_process	FAD biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0003919	molecular_function	FMN adenylyltransferase activity
B	0005524	molecular_function	ATP binding
B	0005575	cellular_component	cellular_component
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006747	biological_process	FAD biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0003919	molecular_function	FMN adenylyltransferase activity
C	0005524	molecular_function	ATP binding
C	0005575	cellular_component	cellular_component
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0006747	biological_process	FAD biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0003824	molecular_function	catalytic activity
D	0003919	molecular_function	FMN adenylyltransferase activity
D	0005524	molecular_function	ATP binding
D	0005575	cellular_component	cellular_component
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0006747	biological_process	FAD biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0000287	molecular_function	magnesium ion binding
E	0003824	molecular_function	catalytic activity
E	0003919	molecular_function	FMN adenylyltransferase activity
E	0005524	molecular_function	ATP binding
E	0005575	cellular_component	cellular_component
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005829	cellular_component	cytosol
E	0006747	biological_process	FAD biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0000287	molecular_function	magnesium ion binding
F	0003824	molecular_function	catalytic activity
F	0003919	molecular_function	FMN adenylyltransferase activity
F	0005524	molecular_function	ATP binding
F	0005575	cellular_component	cellular_component
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005829	cellular_component	cytosol
F	0006747	biological_process	FAD biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016779	molecular_function	nucleotidyltransferase activity
F	0016787	molecular_function	hydrolase activity
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	27
Details	BINDING SITE FOR RESIDUE APC A 305

Chain	Residue
A	SER60
A	ILE108
A	ILE162
A	GLY163
A	ASP168
A	TYR216
A	SER222
A	LEU223
A	GLU296
A	ARG297
A	FMN306
A	TYR61
A	MG307
A	HOH315
A	HOH336
A	HOH492
A	HOH495
A	HOH1787
A	HOH1788
A	HOH1789
A	ASN62
A	GLY64
A	LYS65
A	ASP66
A	CYS67
A	VAL106
A	PHE107

site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE FMN A 306

Chain	Residue
A	SER60
A	THR142
A	MET143
A	PHE147
A	ILE162
A	THR180
A	ASP181
A	TRP184
A	ARG189
A	APC305
A	HOH393
A	HOH403
A	HOH757
A	HOH934
A	HOH1280

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 307

Chain	Residue
A	ASP66
A	APC305
A	HOH315
A	HOH336
A	HOH1788

site_id	AC4
Number of Residues	25
Details	BINDING SITE FOR RESIDUE APC B 305

Chain	Residue
B	SER60
B	TYR61
B	ASN62
B	LYS65
B	ASP66
B	CYS67
B	VAL106
B	PHE107
B	ILE108
B	ILE162
B	GLY163
B	ASP168
B	SER222
B	LEU223
B	GLU296
B	ARG297
B	MG307
B	HOH313
B	HOH315
B	HOH318
B	HOH323
B	HOH362
B	HOH368
B	HOH1026
B	HOH1202

site_id	AC5
Number of Residues	13
Details	BINDING SITE FOR RESIDUE FMN B 306

Chain	Residue
B	SER60
B	MET143
B	PHE147
B	ILE162
B	THR180
B	ASP181
B	TRP184
B	PHE187
B	ARG189
B	HOH346
B	HOH614
B	HOH1598
B	HOH1692

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 307

Chain	Residue
B	ASP66
B	APC305
B	HOH313
B	HOH315

site_id	AC7
Number of Residues	24
Details	BINDING SITE FOR RESIDUE APC C 305

Chain	Residue
C	ILE162
C	GLY163
C	TYR216
C	SER222
C	LEU223
C	FMN306
C	MG307
C	HOH327
C	HOH331
C	HOH433
C	HOH546
C	HOH787
C	HOH834
C	HOH1201
C	SER60
C	TYR61
C	ASN62
C	GLY64
C	LYS65
C	ASP66
C	CYS67
C	VAL106
C	PHE107
C	ILE108

site_id	AC8
Number of Residues	15
Details	BINDING SITE FOR RESIDUE FMN C 306

Chain	Residue
C	SER60
C	THR142
C	MET143
C	PHE147
C	ILE162
C	THR180
C	ASP181
C	TRP184
C	ARG189
C	APC305
C	HOH782
C	HOH974
C	HOH1418
C	HOH1544
C	HOH1727

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 307

Chain	Residue
C	ASP66
C	APC305
C	HOH316
C	HOH331
C	HOH1201

site_id	BC1
Number of Residues	24
Details	BINDING SITE FOR RESIDUE APC D 305

Chain	Residue
D	SER60
D	ASN62
D	GLY64
D	LYS65
D	ASP66
D	CYS67
D	VAL106
D	ILE108
D	ILE162
D	GLY163
D	TYR216
D	THR221
D	SER222
D	LEU223
D	FMN306
D	MG307
D	HOH313
D	HOH315
D	HOH317
D	HOH318
D	HOH352
D	HOH957
D	HOH1119
D	HOH1782

site_id	BC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE FMN D 306

Chain	Residue
D	SER60
D	THR142
D	MET143
D	ILE160
D	ILE162
D	THR180
D	ASP181
D	TRP184
D	ARG189
D	APC305
D	HOH349
D	HOH798
D	HOH938
D	HOH1283
D	HOH1527

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 307

Chain	Residue
D	ASP66
D	APC305
D	HOH315
D	HOH317
D	HOH1782

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 308

Chain	Residue
D	LYS115
D	ASN119
D	ALA270
D	ASP271
D	HOH1160

site_id	BC5
Number of Residues	24
Details	BINDING SITE FOR RESIDUE APC E 305

Chain	Residue
E	SER60
E	ASN62
E	GLY64
E	LYS65
E	ASP66
E	CYS67
E	VAL106
E	PHE107
E	ILE108
E	ILE162
E	GLY163
E	TYR216
E	SER222
E	LEU223
E	FMN306
E	MG307
E	HOH312
E	HOH313
E	HOH327
E	HOH347
E	HOH355
E	HOH770
E	HOH1110
E	HOH1647

site_id	BC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE FMN E 306

Chain	Residue
E	SER60
E	PHE147
E	ILE160
E	ILE162
E	ILE164
E	ASP168
E	PRO169
E	THR180
E	ASP181
E	TRP184
E	PHE187
E	ARG189
E	ARG297
E	APC305
E	HOH325
E	HOH1412
E	HOH1475

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG E 307

Chain	Residue
E	ASP66
E	APC305
E	HOH312
E	HOH313
E	HOH327

site_id	BC8
Number of Residues	27
Details	BINDING SITE FOR RESIDUE APC F 305

Chain	Residue
F	SER60
F	TYR61
F	ASN62
F	LYS65
F	ASP66
F	CYS67
F	VAL106
F	PHE107
F	ILE108
F	MET143
F	ILE162
F	GLY163
F	ASP168
F	SER222
F	LEU223
F	GLU296
F	ARG297
F	MG307
F	HOH309
F	HOH320
F	HOH323
F	HOH324
F	HOH355
F	HOH426
F	HOH618
F	HOH1203
F	HOH1735

site_id	BC9
Number of Residues	11
Details	BINDING SITE FOR RESIDUE FMN F 306

Chain	Residue
F	THR142
F	MET143
F	PHE147
F	ILE160
F	ILE162
F	THR180
F	ASP181
F	TRP184
F	ARG189
F	HOH345
F	HOH1423

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 307

Chain	Residue
F	ASP66
F	APC305
F	HOH320
F	HOH426

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)