3FUZ
Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex with L-glutamate in space group P1
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU A 301 |
| Chain | Residue |
| A | HOH4 |
| A | GLY673 |
| A | SER674 |
| A | THR675 |
| A | GLU723 |
| A | HOH15 |
| A | HOH30 |
| A | HOH40 |
| A | TYR474 |
| A | PRO501 |
| A | LEU502 |
| A | THR503 |
| A | ARG508 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1 |
| Chain | Residue |
| A | HOH74 |
| A | HOH90 |
| A | HOH165 |
| A | ARG444 |
| A | LEU468 |
| B | ARG704 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 3 |
| Chain | Residue |
| A | HOH103 |
| A | LYS664 |
| A | LYS782 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GLU B 302 |
| Chain | Residue |
| A | HOH6 |
| A | HOH9 |
| A | HOH21 |
| A | HOH52 |
| B | TYR474 |
| B | PRO501 |
| B | LEU502 |
| B | THR503 |
| B | ARG508 |
| B | GLY673 |
| B | SER674 |
| B | THR675 |
| B | GLU723 |
| B | TYR749 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2 |
| Chain | Residue |
| B | ARG444 |
| B | VAL466 |
| B | LYS467 |
| B | LEU468 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21893069","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZNS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FUZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by PKC","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKC","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
