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3FRC

Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118

Functional Information from GO Data
ChainGOidnamespacecontents
A0004364molecular_functionglutathione transferase activity
A0016740molecular_functiontransferase activity
B0004364molecular_functionglutathione transferase activity
B0016740molecular_functiontransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE 0HG A 212
ChainResidue
ATYR9
AASN111
AHOH229
AHOH267
AHOH271
AHOH291
AHOH312
BPHE42
BLYS46
BASP105
APHE10
ALYS15
AGLU57
AGLN58
AVAL59
APRO60
AGLN71
ASER72

site_idAC2
Number of Residues18
DetailsBINDING SITE FOR RESIDUE 0HG B 212
ChainResidue
APHE42
AASP105
BTYR9
BPHE10
BLYS15
BPHE45
BGLU57
BGLN58
BVAL59
BGLN71
BSER72
BASN111
BLEU115
BTYR211
BHOH235
BHOH306
BHOH311
BHOH330

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000305|PubMed:12972411
ChainResidueDetails
AGLN58
AGLN71
ALYS117
ATHR121
BGLN58
BGLN71
BLYS117
BTHR121

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0007744|PDB:3FR9
ChainResidueDetails
AASP105
BASP105

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PDB entries from 2024-10-30

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