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3FQK

Hepatitis C virus polymerase NS5B (BK 1-570) with HCV-796 inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
A0003968molecular_functionRNA-dependent RNA polymerase activity
A0039694biological_processviral RNA genome replication
B0003723molecular_functionRNA binding
B0003968molecular_functionRNA-dependent RNA polymerase activity
B0039694biological_processviral RNA genome replication
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE 79Z A 571
ChainResidue
APHE193
ALEU384
AMET414
ATYR415
ATYR448
AARG200
ALEU204
ALEU314
AASN316
AILE363
ASER365
ACYS366
ASER368

site_idAC2
Number of Residues13
DetailsBINDING SITE FOR RESIDUE 79Z B 571
ChainResidue
BARG200
BLEU204
BLEU314
BASN316
BILE363
BSER365
BCYS366
BSER368
BLEU384
BMET414
BTYR415
BTYR448
BHOH845

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000305|PubMed:10557268, ECO:0000305|PubMed:11884572
ChainResidueDetails
AASP220
AASP318
AASP319
BASP220
BASP318
BASP319

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: Phosphoserine; by host => ECO:0000250|UniProtKB:P26662
ChainResidueDetails
ASER29
ASER42
BSER29
BSER42

227344

PDB entries from 2024-11-13

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