3FQD
Crystal Structure of the S. pombe Rat1-Rai1 Complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0004534 | molecular_function | 5'-3' RNA exonuclease activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000448 | biological_process | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| B | 0000956 | biological_process | nuclear-transcribed mRNA catabolic process |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005829 | cellular_component | cytosol |
| B | 0006397 | biological_process | mRNA processing |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019003 | molecular_function | GDP binding |
| B | 0034353 | molecular_function | mRNA 5'-diphosphatase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0090730 | cellular_component | Las1 complex |
| B | 0110152 | molecular_function | RNA NAD+-cap (NAD+-forming) hydrolase activity |
| B | 0110155 | biological_process | NAD-cap decapping |
| B | 0140432 | molecular_function | 5'-hydroxyl dinucleotide hydrolase activity |
| B | 1990174 | molecular_function | phosphodiesterase decapping endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B1000 |
| Chain | Residue |
| B | GLU150 |
| B | ASP201 |
| B | GLU239 |
| B | LEU240 |
| B | HOH1044 |
| B | HOH1162 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B1001 |
| Chain | Residue |
| B | TYR246 |
| B | MSE297 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 35 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O70348","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19194460","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18257517","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
