3FQ3
Crystal structure of inorganic phosphatase from brucella melitensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006796 | biological_process | phosphate-containing compound metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006796 | biological_process | phosphate-containing compound metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006796 | biological_process | phosphate-containing compound metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006796 | biological_process | phosphate-containing compound metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006796 | biological_process | phosphate-containing compound metabolic process |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006796 | biological_process | phosphate-containing compound metabolic process |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006796 | biological_process | phosphate-containing compound metabolic process |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0000287 | molecular_function | magnesium ion binding |
| H | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006796 | biological_process | phosphate-containing compound metabolic process |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0046872 | molecular_function | metal ion binding |
| I | 0000287 | molecular_function | magnesium ion binding |
| I | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0006796 | biological_process | phosphate-containing compound metabolic process |
| I | 0016787 | molecular_function | hydrolase activity |
| I | 0046872 | molecular_function | metal ion binding |
| J | 0000287 | molecular_function | magnesium ion binding |
| J | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0006796 | biological_process | phosphate-containing compound metabolic process |
| J | 0016787 | molecular_function | hydrolase activity |
| J | 0046872 | molecular_function | metal ion binding |
| K | 0000287 | molecular_function | magnesium ion binding |
| K | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0006796 | biological_process | phosphate-containing compound metabolic process |
| K | 0016787 | molecular_function | hydrolase activity |
| K | 0046872 | molecular_function | metal ion binding |
| L | 0000287 | molecular_function | magnesium ion binding |
| L | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0006796 | biological_process | phosphate-containing compound metabolic process |
| L | 0016787 | molecular_function | hydrolase activity |
| L | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 177 |
| Chain | Residue |
| A | ASN76 |
| A | THR77 |
| A | ARG78 |
| A | ARG117 |
| A | TYR118 |
| C | PHE45 |
| C | TYR47 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 A 178 |
| Chain | Residue |
| A | LYS105 |
| A | LYS143 |
| A | HOH768 |
| A | HOH999 |
| A | HOH1491 |
| A | HOH1540 |
| A | HOH1573 |
| A | HOH2026 |
| A | LYS30 |
| A | ASP103 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 177 |
| Chain | Residue |
| B | ASN76 |
| B | THR77 |
| B | ARG78 |
| B | ARG117 |
| B | TYR118 |
| D | PHE45 |
| D | TYR47 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 B 178 |
| Chain | Residue |
| B | LYS30 |
| B | ASP103 |
| B | LYS105 |
| B | LYS143 |
| B | HOH519 |
| B | HOH538 |
| B | HOH693 |
| B | HOH734 |
| B | HOH1149 |
| B | HOH1615 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 C 177 |
| Chain | Residue |
| C | ASN76 |
| C | THR77 |
| C | ARG78 |
| C | ARG117 |
| C | TYR118 |
| C | HOH181 |
| E | PHE45 |
| E | TYR47 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 C 178 |
| Chain | Residue |
| C | LYS30 |
| C | ASP103 |
| C | LYS105 |
| C | LYS143 |
| C | HOH185 |
| C | HOH421 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 D 177 |
| Chain | Residue |
| D | ASN76 |
| D | THR77 |
| D | ARG78 |
| D | ARG117 |
| D | TYR118 |
| D | HOH192 |
| F | PHE45 |
| F | TYR47 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 D 178 |
| Chain | Residue |
| D | LYS30 |
| D | ASP103 |
| D | LYS105 |
| D | LYS143 |
| D | HOH208 |
| D | HOH394 |
| D | HOH1783 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 E 177 |
| Chain | Residue |
| A | PHE45 |
| A | TYR47 |
| E | ASN76 |
| E | THR77 |
| E | ARG78 |
| E | ARG117 |
| E | TYR118 |
| E | HOH1176 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 E 178 |
| Chain | Residue |
| E | LYS30 |
| E | ASP103 |
| E | LYS105 |
| E | LYS143 |
| E | HOH1156 |
| E | HOH1589 |
| E | HOH1744 |
| E | HOH2009 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 F 177 |
| Chain | Residue |
| B | PHE45 |
| B | TYR47 |
| F | ASN76 |
| F | THR77 |
| F | ARG78 |
| F | ARG117 |
| F | TYR118 |
| F | HOH803 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 F 178 |
| Chain | Residue |
| F | LYS30 |
| F | ASP103 |
| F | LYS105 |
| F | LYS143 |
| F | HOH212 |
| F | HOH1803 |
| F | HOH1978 |
| F | HOH2062 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 G 177 |
| Chain | Residue |
| G | TYR118 |
| G | HOH317 |
| I | PHE45 |
| I | TYR47 |
| G | ASN76 |
| G | THR77 |
| G | ARG78 |
| G | ARG117 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 H 177 |
| Chain | Residue |
| H | ASN76 |
| H | THR77 |
| H | ARG78 |
| H | ARG117 |
| H | TYR118 |
| H | HOH1896 |
| J | PHE45 |
| J | TYR47 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 I 177 |
| Chain | Residue |
| I | ASN76 |
| I | THR77 |
| I | ARG78 |
| I | ARG117 |
| I | TYR118 |
| I | HOH441 |
| K | PHE45 |
| K | TYR47 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 J 177 |
| Chain | Residue |
| J | ASN76 |
| J | THR77 |
| J | ARG78 |
| J | ARG117 |
| J | TYR118 |
| J | HOH1588 |
| L | PHE45 |
| L | TYR47 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 J 178 |
| Chain | Residue |
| J | LYS30 |
| J | ASP103 |
| J | LYS105 |
| J | LYS143 |
| J | HOH959 |
| J | HOH1574 |
| J | HOH1886 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 K 177 |
| Chain | Residue |
| G | PHE45 |
| G | TYR47 |
| K | ASN76 |
| K | THR77 |
| K | ARG78 |
| K | ARG117 |
| K | TYR118 |
| K | HOH595 |
| site_id | CC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 K 178 |
| Chain | Residue |
| K | LYS30 |
| K | ASP103 |
| K | LYS105 |
| K | TYR142 |
| K | LYS143 |
| K | HOH190 |
| K | HOH451 |
| K | HOH555 |
| K | HOH1699 |
| site_id | CC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 L 177 |
| Chain | Residue |
| H | PHE45 |
| H | TYR47 |
| L | ASN76 |
| L | THR77 |
| L | ARG78 |
| L | ARG117 |
| L | TYR118 |
| L | HOH190 |
| site_id | CC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 L 178 |
| Chain | Residue |
| L | LYS30 |
| L | ASP103 |
| L | LYS105 |
| L | LYS143 |
| L | HOH184 |
| L | HOH1168 |
| L | HOH1937 |
| L | HOH1951 |
| L | HOH2006 |
Functional Information from PROSITE/UniProt
| site_id | PS00387 |
| Number of Residues | 7 |
| Details | PPASE Inorganic pyrophosphatase signature. DGDPIDV |
| Chain | Residue | Details |
| A | ASP66-VAL72 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| A | ASP68 |
| site_id | CSA10 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| J | ASP68 |
| site_id | CSA11 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| K | ASP68 |
| site_id | CSA12 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| L | ASP68 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| B | ASP68 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| C | ASP68 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| D | ASP68 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| E | ASP68 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| F | ASP68 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| G | ASP68 |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| H | ASP68 |
| site_id | CSA9 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| I | ASP68 |
