Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005694 | cellular_component | chromosome |
A | 0006259 | biological_process | DNA metabolic process |
A | 0006265 | biological_process | DNA topological change |
B | 0003677 | molecular_function | DNA binding |
B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
B | 0005524 | molecular_function | ATP binding |
B | 0005694 | cellular_component | chromosome |
B | 0006259 | biological_process | DNA metabolic process |
B | 0006265 | biological_process | DNA topological change |
C | 0003677 | molecular_function | DNA binding |
C | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
C | 0005524 | molecular_function | ATP binding |
C | 0006265 | biological_process | DNA topological change |
D | 0003677 | molecular_function | DNA binding |
D | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
D | 0005524 | molecular_function | ATP binding |
D | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
site_id | 1 |
Number of Residues | |
Details | |
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE MFX F 0 |
Chain | Residue |
B | GLY77 |
B | ASP78 |
B | SER79 |
B | SER80 |
F | DA1 |
G | DT15 |
H | DT4 |
H | DA5 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MFX H 0 |
Chain | Residue |
A | SER79 |
A | SER80 |
F | DC4 |
F | DA5 |
H | DG1 |
A | GLY77 |
Functional Information from PROSITE/UniProt
site_id | PS00177 |
Number of Residues | 9 |
Details | TOPOISOMERASE_II DNA topoisomerase II signature. LVEGDSAGG |
Chain | Residue | Details |
C | LEU431-GLY439 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
C | GLU433 | |
C | ASP506 | |
C | ASP508 | |
D | GLU433 | |
D | ASP506 | |
D | ASP508 | |
Chain | Residue | Details |
C | LYS458 | |
B | LYS93 | |
C | ASN461 | |
C | HIS513 | |
C | ARG629 | |
D | LYS458 | |
D | ASN461 | |
D | HIS513 | |
D | ARG629 | |
B | ARG87 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | SITE: Transition state stabilizer |
Chain | Residue | Details |
A | ARG117 | |
B | ARG117 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ab4 |
Chain | Residue | Details |
A | TYR118 | |
A | ARG28 | |
A | HIS74 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ab4 |
Chain | Residue | Details |
B | TYR118 | |
B | ARG28 | |
B | HIS74 | |