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3FNS

Crystal structure of histo-aspartic protease (HAP) from Plasmodium Falciparum

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
B0004190molecular_functionaspartic-type endopeptidase activity
B0006508biological_processproteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 329
ChainResidue
AHIS32
AASP215
AHOH374
BGLU278

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE ZN A 330
ChainResidue
AASP195
AHIS198

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ZN A 331
ChainResidue
AASP127
AHIS186
AASP187

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 332
ChainResidue
AGLU48
AGLU51
BGLU51
BHOH375

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 329
ChainResidue
AGLU278
AHOH336
BHIS32
BASP215

site_idAC6
Number of Residues2
DetailsBINDING SITE FOR RESIDUE ZN B 330
ChainResidue
BASP195
BHIS198

Catalytic Information from CSA
site_idCSA1
Number of Residues4
DetailsAnnotated By Reference To The Literature 1am5
ChainResidueDetails
AASP215
ASER35
ATHR218
AHIS32

site_idCSA10
Number of Residues1
DetailsAnnotated By Reference To The Literature 1am5
ChainResidueDetails
BASP215

site_idCSA2
Number of Residues4
DetailsAnnotated By Reference To The Literature 1am5
ChainResidueDetails
BASP215
BSER35
BTHR218
BHIS32

site_idCSA3
Number of Residues3
DetailsAnnotated By Reference To The Literature 1am5
ChainResidueDetails
AASP215
ASER35
AHIS32

site_idCSA4
Number of Residues3
DetailsAnnotated By Reference To The Literature 1am5
ChainResidueDetails
BASP215
BSER35
BHIS32

site_idCSA5
Number of Residues4
DetailsAnnotated By Reference To The Literature 1am5
ChainResidueDetails
AASP215
ATHR218
AHIS32
ATHR33

site_idCSA6
Number of Residues4
DetailsAnnotated By Reference To The Literature 1am5
ChainResidueDetails
BASP215
BTHR218
BHIS32
BTHR33

site_idCSA7
Number of Residues1
DetailsAnnotated By Reference To The Literature 1am5
ChainResidueDetails
AHIS32

site_idCSA8
Number of Residues1
DetailsAnnotated By Reference To The Literature 1am5
ChainResidueDetails
BHIS32

site_idCSA9
Number of Residues1
DetailsAnnotated By Reference To The Literature 1am5
ChainResidueDetails
AASP215

227111

PDB entries from 2024-11-06

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