3FIU

Structure of NMN synthetase from Francisella tularensis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003952	molecular_function	NAD+ synthase (glutamine-hydrolyzing) activity
A	0004359	molecular_function	glutaminase activity
A	0005737	cellular_component	cytoplasm
A	0008795	molecular_function	NAD+ synthase activity
A	0009435	biological_process	NAD biosynthetic process
B	0003952	molecular_function	NAD+ synthase (glutamine-hydrolyzing) activity
B	0004359	molecular_function	glutaminase activity
B	0005737	cellular_component	cytoplasm
B	0008795	molecular_function	NAD+ synthase activity
B	0009435	biological_process	NAD biosynthetic process
C	0003952	molecular_function	NAD+ synthase (glutamine-hydrolyzing) activity
C	0004359	molecular_function	glutaminase activity
C	0005737	cellular_component	cytoplasm
C	0008795	molecular_function	NAD+ synthase activity
C	0009435	biological_process	NAD biosynthetic process
D	0003952	molecular_function	NAD+ synthase (glutamine-hydrolyzing) activity
D	0004359	molecular_function	glutaminase activity
D	0005737	cellular_component	cytoplasm
D	0008795	molecular_function	NAD+ synthase activity
D	0009435	biological_process	NAD biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A5001

Chain	Residue
A	ASP41
A	GLU147
A	HOH251
A	AMP3001
A	POP4001

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A5002

Chain	Residue
A	AMP3001
A	POP4001
A	SER193
A	NA250
A	HOH253
A	HOH254

---

site_id	AC3
Number of Residues	21
Details	BINDING SITE FOR RESIDUE AMP A3001

Chain	Residue
A	GLY35
A	LEU36
A	SER37
A	SER42
A	LEU59
A	LEU61
A	ARG124
A	THR142
A	GLU147
A	ASP158
A	SER193
A	ALA194
A	NA250
A	HOH254
A	HOH259
A	HOH280
A	HOH328
A	HOH377
A	POP4001
A	MG5001
A	MG5002

---

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE POP A4001

Chain	Residue
A	SER37
A	GLY39
A	ILE40
A	ASP41
A	SER42
A	GLU147
A	LYS171
A	PRO192
A	SER193
A	NA250
A	HOH251
A	HOH253
A	HOH254
A	HOH268
A	AMP3001
A	MG5001
A	MG5002

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 250

Chain	Residue
A	SER193
A	ASP202
A	HOH750
A	AMP3001
A	POP4001
A	MG5002

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B5001

Chain	Residue
B	ASP41
B	GLU147
B	HOH252
B	AMP3001
B	POP4001

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B5002

Chain	Residue
B	SER193
B	NA250
B	HOH253
B	HOH255
B	AMP3001
B	POP4001

---

site_id	AC8
Number of Residues	24
Details	BINDING SITE FOR RESIDUE AMP B3001

Chain	Residue
B	GLY35
B	LEU36
B	SER37
B	SER42
B	LEU59
B	LEU61
B	ASN66
B	ARG124
B	THR142
B	GLU147
B	ASP158
B	SER193
B	ALA194
B	NA250
B	HOH252
B	HOH255
B	HOH279
B	HOH284
B	HOH287
B	HOH297
B	HOH511
B	POP4001
B	MG5001
B	MG5002

---

site_id	AC9
Number of Residues	17
Details	BINDING SITE FOR RESIDUE POP B4001

Chain	Residue
B	NA250
B	HOH252
B	HOH253
B	HOH255
B	HOH273
B	AMP3001
B	MG5001
B	MG5002
B	SER37
B	GLY39
B	ILE40
B	ASP41
B	SER42
B	GLU147
B	LYS171
B	PRO192
B	SER193

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA B 250

Chain	Residue
B	SER193
B	ASP202
B	HOH616
B	AMP3001
B	POP4001
B	MG5002

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C5001

Chain	Residue
C	ASP41
C	GLU147
C	HOH251
C	AMP3001
C	POP4001

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C5002

Chain	Residue
C	SER193
C	NA250
C	HOH252
C	HOH254
C	AMP3001
C	POP4001

---

site_id	BC4
Number of Residues	22
Details	BINDING SITE FOR RESIDUE AMP C3001

Chain	Residue
C	GLY35
C	LEU36
C	SER37
C	SER42
C	LEU59
C	LEU61
C	ARG124
C	THR142
C	GLU147
C	ASP158
C	SER193
C	ALA194
C	NA250
C	HOH254
C	HOH255
C	HOH297
C	HOH300
C	HOH305
C	HOH329
C	POP4001
C	MG5001
C	MG5002

---

site_id	BC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE POP C4001

Chain	Residue
C	SER37
C	GLY39
C	ILE40
C	ASP41
C	SER42
C	GLU147
C	LYS171
C	PRO192
C	SER193
C	NA250
C	HOH252
C	HOH254
C	HOH256
C	AMP3001
C	MG5001
C	MG5002

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA C 250

Chain	Residue
C	SER193
C	ASP202
C	HOH550
C	AMP3001
C	POP4001
C	MG5002

---

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D5001

Chain	Residue
D	ASP41
D	GLU147
D	NA250
D	HOH251
D	AMP3001
D	POP4001

---

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D5002

Chain	Residue
D	SER193
D	NA250
D	HOH252
D	HOH253
D	AMP3001
D	POP4001

---

site_id	BC9
Number of Residues	22
Details	BINDING SITE FOR RESIDUE AMP D3001

Chain	Residue
D	GLY35
D	LEU36
D	SER37
D	SER42
D	LEU59
D	LEU61
D	ARG124
D	THR142
D	GLU147
D	ASP158
D	SER193
D	ALA194
D	NA250
D	HOH251
D	HOH253
D	HOH265
D	HOH272
D	HOH322
D	HOH484
D	POP4001
D	MG5001
D	MG5002

---

site_id	CC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE POP D4001

Chain	Residue
D	SER37
D	GLY39
D	ILE40
D	ASP41
D	SER42
D	GLU147
D	LYS171
D	PRO192
D	SER193
D	NA250
D	HOH251
D	HOH252
D	HOH253
D	HOH255
D	AMP3001
D	MG5001
D	MG5002

---

site_id	CC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA D 250

Chain	Residue
D	SER193
D	ASP202
D	HOH500
D	AMP3001
D	POP4001
D	MG5001
D	MG5002

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