3FIU
Structure of NMN synthetase from Francisella tularensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003952 | molecular_function | NAD+ synthase (glutamine-hydrolyzing) activity |
| A | 0004359 | molecular_function | glutaminase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008795 | molecular_function | NAD+ synthase activity |
| A | 0009435 | biological_process | NAD+ biosynthetic process |
| B | 0003952 | molecular_function | NAD+ synthase (glutamine-hydrolyzing) activity |
| B | 0004359 | molecular_function | glutaminase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008795 | molecular_function | NAD+ synthase activity |
| B | 0009435 | biological_process | NAD+ biosynthetic process |
| C | 0003952 | molecular_function | NAD+ synthase (glutamine-hydrolyzing) activity |
| C | 0004359 | molecular_function | glutaminase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008795 | molecular_function | NAD+ synthase activity |
| C | 0009435 | biological_process | NAD+ biosynthetic process |
| D | 0003952 | molecular_function | NAD+ synthase (glutamine-hydrolyzing) activity |
| D | 0004359 | molecular_function | glutaminase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008795 | molecular_function | NAD+ synthase activity |
| D | 0009435 | biological_process | NAD+ biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A5001 |
| Chain | Residue |
| A | ASP41 |
| A | GLU147 |
| A | HOH251 |
| A | AMP3001 |
| A | POP4001 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A5002 |
| Chain | Residue |
| A | AMP3001 |
| A | POP4001 |
| A | SER193 |
| A | NA250 |
| A | HOH253 |
| A | HOH254 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE AMP A3001 |
| Chain | Residue |
| A | GLY35 |
| A | LEU36 |
| A | SER37 |
| A | SER42 |
| A | LEU59 |
| A | LEU61 |
| A | ARG124 |
| A | THR142 |
| A | GLU147 |
| A | ASP158 |
| A | SER193 |
| A | ALA194 |
| A | NA250 |
| A | HOH254 |
| A | HOH259 |
| A | HOH280 |
| A | HOH328 |
| A | HOH377 |
| A | POP4001 |
| A | MG5001 |
| A | MG5002 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE POP A4001 |
| Chain | Residue |
| A | SER37 |
| A | GLY39 |
| A | ILE40 |
| A | ASP41 |
| A | SER42 |
| A | GLU147 |
| A | LYS171 |
| A | PRO192 |
| A | SER193 |
| A | NA250 |
| A | HOH251 |
| A | HOH253 |
| A | HOH254 |
| A | HOH268 |
| A | AMP3001 |
| A | MG5001 |
| A | MG5002 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 250 |
| Chain | Residue |
| A | SER193 |
| A | ASP202 |
| A | HOH750 |
| A | AMP3001 |
| A | POP4001 |
| A | MG5002 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B5001 |
| Chain | Residue |
| B | ASP41 |
| B | GLU147 |
| B | HOH252 |
| B | AMP3001 |
| B | POP4001 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B5002 |
| Chain | Residue |
| B | SER193 |
| B | NA250 |
| B | HOH253 |
| B | HOH255 |
| B | AMP3001 |
| B | POP4001 |
| site_id | AC8 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE AMP B3001 |
| Chain | Residue |
| B | GLY35 |
| B | LEU36 |
| B | SER37 |
| B | SER42 |
| B | LEU59 |
| B | LEU61 |
| B | ASN66 |
| B | ARG124 |
| B | THR142 |
| B | GLU147 |
| B | ASP158 |
| B | SER193 |
| B | ALA194 |
| B | NA250 |
| B | HOH252 |
| B | HOH255 |
| B | HOH279 |
| B | HOH284 |
| B | HOH287 |
| B | HOH297 |
| B | HOH511 |
| B | POP4001 |
| B | MG5001 |
| B | MG5002 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE POP B4001 |
| Chain | Residue |
| B | NA250 |
| B | HOH252 |
| B | HOH253 |
| B | HOH255 |
| B | HOH273 |
| B | AMP3001 |
| B | MG5001 |
| B | MG5002 |
| B | SER37 |
| B | GLY39 |
| B | ILE40 |
| B | ASP41 |
| B | SER42 |
| B | GLU147 |
| B | LYS171 |
| B | PRO192 |
| B | SER193 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 250 |
| Chain | Residue |
| B | SER193 |
| B | ASP202 |
| B | HOH616 |
| B | AMP3001 |
| B | POP4001 |
| B | MG5002 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C5001 |
| Chain | Residue |
| C | ASP41 |
| C | GLU147 |
| C | HOH251 |
| C | AMP3001 |
| C | POP4001 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C5002 |
| Chain | Residue |
| C | SER193 |
| C | NA250 |
| C | HOH252 |
| C | HOH254 |
| C | AMP3001 |
| C | POP4001 |
| site_id | BC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE AMP C3001 |
| Chain | Residue |
| C | GLY35 |
| C | LEU36 |
| C | SER37 |
| C | SER42 |
| C | LEU59 |
| C | LEU61 |
| C | ARG124 |
| C | THR142 |
| C | GLU147 |
| C | ASP158 |
| C | SER193 |
| C | ALA194 |
| C | NA250 |
| C | HOH254 |
| C | HOH255 |
| C | HOH297 |
| C | HOH300 |
| C | HOH305 |
| C | HOH329 |
| C | POP4001 |
| C | MG5001 |
| C | MG5002 |
| site_id | BC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE POP C4001 |
| Chain | Residue |
| C | SER37 |
| C | GLY39 |
| C | ILE40 |
| C | ASP41 |
| C | SER42 |
| C | GLU147 |
| C | LYS171 |
| C | PRO192 |
| C | SER193 |
| C | NA250 |
| C | HOH252 |
| C | HOH254 |
| C | HOH256 |
| C | AMP3001 |
| C | MG5001 |
| C | MG5002 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 250 |
| Chain | Residue |
| C | SER193 |
| C | ASP202 |
| C | HOH550 |
| C | AMP3001 |
| C | POP4001 |
| C | MG5002 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D5001 |
| Chain | Residue |
| D | ASP41 |
| D | GLU147 |
| D | NA250 |
| D | HOH251 |
| D | AMP3001 |
| D | POP4001 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D5002 |
| Chain | Residue |
| D | SER193 |
| D | NA250 |
| D | HOH252 |
| D | HOH253 |
| D | AMP3001 |
| D | POP4001 |
| site_id | BC9 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE AMP D3001 |
| Chain | Residue |
| D | GLY35 |
| D | LEU36 |
| D | SER37 |
| D | SER42 |
| D | LEU59 |
| D | LEU61 |
| D | ARG124 |
| D | THR142 |
| D | GLU147 |
| D | ASP158 |
| D | SER193 |
| D | ALA194 |
| D | NA250 |
| D | HOH251 |
| D | HOH253 |
| D | HOH265 |
| D | HOH272 |
| D | HOH322 |
| D | HOH484 |
| D | POP4001 |
| D | MG5001 |
| D | MG5002 |
| site_id | CC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE POP D4001 |
| Chain | Residue |
| D | SER37 |
| D | GLY39 |
| D | ILE40 |
| D | ASP41 |
| D | SER42 |
| D | GLU147 |
| D | LYS171 |
| D | PRO192 |
| D | SER193 |
| D | NA250 |
| D | HOH251 |
| D | HOH252 |
| D | HOH253 |
| D | HOH255 |
| D | AMP3001 |
| D | MG5001 |
| D | MG5002 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA D 250 |
| Chain | Residue |
| D | SER193 |
| D | ASP202 |
| D | HOH500 |
| D | AMP3001 |
| D | POP4001 |
| D | MG5001 |
| D | MG5002 |
