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3FIE

Crystal structure of Clostridium botulinum neurotoxin serotype F catalytic domain with an inhibitor (inh1)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004222molecular_functionmetalloendopeptidase activity
A0006508biological_processproteolysis
A0008270molecular_functionzinc ion binding
B0004222molecular_functionmetalloendopeptidase activity
B0006508biological_processproteolysis
B0008270molecular_functionzinc ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 428
ChainResidue
AHIS227
AHIS231
AGLU266
CDCY58

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 822
ChainResidue
BHIS227
BHIS231
BGLU266
DDCY58

Functional Information from PROSITE/UniProt
site_idPS00142
Number of Residues10
DetailsZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. SLAHELIHAL
ChainResidueDetails
ASER224-LEU233

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10095
ChainResidueDetails
AGLU228
BGLU228

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10095, ECO:0000269|PubMed:19543288, ECO:0007744|PDB:3FIE, ECO:0007744|PDB:3FII
ChainResidueDetails
AHIS227
AHIS231
BHIS227
BHIS231

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:19543288, ECO:0007744|PDB:3FIE, ECO:0007744|PDB:3FII
ChainResidueDetails
AGLU266
BGLU266

Catalytic Information from CSA
site_idCSA1
Number of Residues3
DetailsAnnotated By Reference To The Literature 1i1e
ChainResidueDetails
ATYR368
AGLU266
AARG365

site_idCSA2
Number of Residues3
DetailsAnnotated By Reference To The Literature 1i1e
ChainResidueDetails
BTYR368
BGLU266
BARG365

226707

PDB entries from 2024-10-30

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