3FHK

Crystal structure of APC1446, B.subtilis YphP disulfide isomerase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003756	molecular_function	protein disulfide isomerase activity
A	0006979	biological_process	response to oxidative stress
A	0016491	molecular_function	oxidoreductase activity
A	0033194	biological_process	response to hydroperoxide
A	0045454	biological_process	cell redox homeostasis
D	0003756	molecular_function	protein disulfide isomerase activity
D	0006979	biological_process	response to oxidative stress
D	0016491	molecular_function	oxidoreductase activity
D	0033194	biological_process	response to hydroperoxide
D	0045454	biological_process	cell redox homeostasis
E	0003756	molecular_function	protein disulfide isomerase activity
E	0006979	biological_process	response to oxidative stress
E	0016491	molecular_function	oxidoreductase activity
E	0033194	biological_process	response to hydroperoxide
E	0045454	biological_process	cell redox homeostasis
F	0003756	molecular_function	protein disulfide isomerase activity
F	0006979	biological_process	response to oxidative stress
F	0016491	molecular_function	oxidoreductase activity
F	0033194	biological_process	response to hydroperoxide
F	0045454	biological_process	cell redox homeostasis

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 145

Chain	Residue
D	GLN85
D	LYS87
D	GLU88
D	HOH154
D	HOH170

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 145

Chain	Residue
A	HOH162
A	HOH203
A	GLN85
A	ASP86
A	LYS87
A	GLU88

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 146

Chain	Residue
A	ALA83
A	ARG94
A	SER104
A	HOH170
A	HOH173
A	HOH225

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 E 145

Chain	Residue
D	LYS87
D	HOH175
E	CYS53
E	GLY54
E	CYS55
E	ARG121

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 146

Chain	Residue
E	ARG94
E	SER104

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 146

Chain	Residue
D	CYS53
D	GLY54
D	CYS55
D	ARG121
E	LYS87

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 147

Chain	Residue
E	GLN85
E	LYS87
E	GLU88
E	HOH154
E	HOH179

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 147

Chain	Residue
A	VAL116
A	HIS117
A	HIS143
A	HOH182
A	HOH187
E	SER-2

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 F 145

Chain	Residue
E	ASP72
E	LYS73
E	HOH172
E	HOH185
F	GLY84
F	ARG94
F	HOH167
F	HOH171

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 147

Chain	Residue
D	ARG94
D	SER104
D	HOH195

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 146

Chain	Residue
F	ASP86
F	LYS87
F	GLU88

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 F 147

Chain	Residue
D	ARG18
D	THR21
F	CYS53
F	GLY54
F	ARG121
F	HOH155

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:24313874

Chain	Residue	Details
A	CYS53
A	CYS55
D	CYS53
D	CYS55
E	CYS53
E	CYS55
F	CYS53
F	CYS55

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: S-bacillithiol cysteine disulfide => ECO:0000269|PubMed:24313874

Chain	Residue	Details
A	CYS53
D	CYS53
E	CYS53
F	CYS53

---