3FFU
Structure of the RNA pyrophosphohydrolase BdRppH in complex with GTP and magnesium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008413 | molecular_function | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0035539 | molecular_function | 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0044715 | molecular_function | 8-oxo-dGDP phosphatase activity |
| A | 0044716 | molecular_function | 8-oxo-GDP phosphatase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0006260 | biological_process | DNA replication |
| B | 0006281 | biological_process | DNA repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008413 | molecular_function | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0035539 | molecular_function | 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0044715 | molecular_function | 8-oxo-dGDP phosphatase activity |
| B | 0044716 | molecular_function | 8-oxo-GDP phosphatase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE GTP B4032 |
| Chain | Residue |
| B | VAL24 |
| B | GLU70 |
| B | GLU74 |
| B | ILE97 |
| B | ILE99 |
| B | PRO133 |
| B | ASN136 |
| B | MG154 |
| B | MG155 |
| B | MG156 |
| B | HOH157 |
| B | ARG40 |
| B | HOH158 |
| B | HOH159 |
| B | HOH161 |
| B | HOH162 |
| B | HOH163 |
| B | ASN44 |
| B | LEU46 |
| B | GLU51 |
| B | PHE52 |
| B | GLY54 |
| B | GLY55 |
| B | LYS56 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE GTP A4033 |
| Chain | Residue |
| A | VAL24 |
| A | ARG40 |
| A | ASN44 |
| A | LEU46 |
| A | GLU51 |
| A | PHE52 |
| A | GLY54 |
| A | GLY55 |
| A | LYS56 |
| A | GLU70 |
| A | GLU74 |
| A | TYR92 |
| A | ILE97 |
| A | PRO133 |
| A | ASN136 |
| A | MG154 |
| A | MG155 |
| A | MG156 |
| A | HOH157 |
| A | HOH159 |
| A | HOH161 |
| A | HOH162 |
| A | HOH163 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 154 |
| Chain | Residue |
| A | GLU70 |
| A | GLU73 |
| A | MG155 |
| A | HOH161 |
| A | HOH162 |
| A | HOH163 |
| A | GTP4033 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MG A 155 |
| Chain | Residue |
| A | GLU70 |
| A | GLU74 |
| A | MG154 |
| A | MG156 |
| A | HOH159 |
| A | HOH160 |
| A | HOH161 |
| A | GTP4033 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 156 |
| Chain | Residue |
| A | GLY54 |
| A | GLU74 |
| A | MG155 |
| A | HOH157 |
| A | HOH158 |
| A | GTP4033 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 154 |
| Chain | Residue |
| B | GLU70 |
| B | GLU73 |
| B | MG155 |
| B | HOH161 |
| B | HOH162 |
| B | HOH163 |
| B | GTP4032 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MG B 155 |
| Chain | Residue |
| B | GLU70 |
| B | GLU73 |
| B | GLU74 |
| B | MG154 |
| B | MG156 |
| B | HOH159 |
| B | HOH160 |
| B | HOH161 |
| B | GTP4032 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 156 |
| Chain | Residue |
| B | GLY54 |
| B | GLU74 |
| B | MG155 |
| B | HOH157 |
| B | HOH158 |
| B | HOH159 |
| B | GTP4032 |
Functional Information from PROSITE/UniProt
| site_id | PS00893 |
| Number of Residues | 22 |
| Details | NUDIX_BOX Nudix box signature. GkiengEtpeeALaRELnEElG |
| Chain | Residue | Details |
| A | GLY55-GLY76 |
