Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0045454 | biological_process | cell redox homeostasis |
A | 0046872 | molecular_function | metal ion binding |
A | 0098869 | biological_process | cellular oxidant detoxification |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0045454 | biological_process | cell redox homeostasis |
B | 0046872 | molecular_function | metal ion binding |
B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 37 |
Details | BINDING SITE FOR RESIDUE FAD A 298 |
Chain | Residue |
A | GLY9 |
A | ARG36 |
A | ARG37 |
A | ASN38 |
A | SER44 |
A | HIS45 |
A | GLY77 |
A | ARG78 |
A | VAL79 |
A | MET108 |
A | GLY109 |
A | SER11 |
A | ASP112 |
A | HIS130 |
A | CYS134 |
A | HIS135 |
A | VAL228 |
A | GLY264 |
A | ASP265 |
A | SER272 |
A | VAL273 |
A | MG301 |
A | TYR12 |
A | HOH305 |
A | HOH310 |
A | HOH315 |
A | HOH319 |
A | HOH341 |
A | HOH342 |
A | HOH358 |
A | HOH486 |
A | ALA13 |
A | VAL31 |
A | ASP32 |
A | ALA33 |
A | GLY34 |
A | GLU35 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 299 |
Chain | Residue |
A | HIS43 |
A | HIS45 |
A | GLU138 |
A | SO4300 |
A | HOH333 |
A | HOH359 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 300 |
Chain | Residue |
A | HIS43 |
A | HIS45 |
A | GLY52 |
A | SO4299 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG A 301 |
Chain | Residue |
A | PHE129 |
A | HIS130 |
A | CYS131 |
A | FAD298 |
site_id | AC5 |
Number of Residues | 36 |
Details | BINDING SITE FOR RESIDUE FAD B 298 |
Chain | Residue |
B | GLY9 |
B | SER11 |
B | TYR12 |
B | ALA13 |
B | VAL31 |
B | ASP32 |
B | ALA33 |
B | GLY34 |
B | GLU35 |
B | ARG37 |
B | ASN38 |
B | SER44 |
B | HIS45 |
B | GLY77 |
B | ARG78 |
B | VAL79 |
B | ALA107 |
B | MET108 |
B | GLY109 |
B | ASP112 |
B | HIS130 |
B | CYS134 |
B | HIS135 |
B | VAL228 |
B | GLY264 |
B | ASP265 |
B | SER272 |
B | VAL273 |
B | HOH304 |
B | HOH308 |
B | HOH311 |
B | HOH312 |
B | HOH368 |
B | HOH392 |
B | HOH401 |
B | HOH413 |
site_id | AC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 B 299 |
Chain | Residue |
B | SER42 |
B | HIS43 |
B | HIS45 |
B | GLU138 |
B | HOH326 |
B | HOH339 |
B | HOH407 |
site_id | AC7 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG B 300 |
Chain | Residue |
B | HIS130 |
B | CYS131 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1tde |
Chain | Residue | Details |
A | HIS135 | |
A | CYS131 | |
A | CYS134 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1tde |
Chain | Residue | Details |
B | HIS135 | |
B | CYS131 | |
B | CYS134 | |