3FAZ
Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase in complex with inosine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0047975 | molecular_function | guanosine phosphorylase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0047975 | molecular_function | guanosine phosphorylase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0047975 | molecular_function | guanosine phosphorylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NOS A 301 |
| Chain | Residue |
| A | TYR90 |
| A | THR244 |
| A | ASN245 |
| A | HIS259 |
| A | VAL262 |
| A | HOH340 |
| A | HOH424 |
| A | SO4706 |
| B | PHE161 |
| A | ALA118 |
| A | ALA119 |
| A | GLY120 |
| A | TYR202 |
| A | GLU203 |
| A | VAL219 |
| A | GLY220 |
| A | MET221 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 706 |
| Chain | Residue |
| A | ARG86 |
| A | HIS88 |
| A | ASN117 |
| A | ALA118 |
| A | SER222 |
| A | NOS301 |
| A | HOH421 |
| A | HOH424 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NOS B 301 |
| Chain | Residue |
| B | TYR90 |
| B | ALA118 |
| B | ALA119 |
| B | GLY120 |
| B | TYR202 |
| B | GLU203 |
| B | VAL219 |
| B | GLY220 |
| B | MET221 |
| B | THR244 |
| B | ASN245 |
| B | HIS259 |
| B | VAL262 |
| B | HOH314 |
| B | HOH320 |
| C | PHE161 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NOS C 301 |
| Chain | Residue |
| C | TYR90 |
| C | ALA118 |
| C | ALA119 |
| C | GLY120 |
| C | TYR202 |
| C | GLU203 |
| C | VAL219 |
| C | GLY220 |
| C | MET221 |
| C | THR244 |
| C | ASN245 |
| C | HIS259 |
| C | VAL262 |
| C | HOH295 |
| C | HOH333 |
| C | SO4706 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 706 |
| Chain | Residue |
| C | ARG86 |
| C | HIS88 |
| C | ASN117 |
| C | ALA118 |
| C | SER222 |
| C | HOH295 |
| C | NOS301 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ula |
| Chain | Residue | Details |
| A | ASN245 | |
| A | HIS88 | |
| A | GLU91 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ula |
| Chain | Residue | Details |
| B | ASN245 | |
| B | HIS88 | |
| B | GLU91 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ula |
| Chain | Residue | Details |
| C | ASN245 | |
| C | HIS88 | |
| C | GLU91 |
