3FAZ
Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase in complex with inosine
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
A | 0009116 | biological_process | nucleoside metabolic process |
A | 0016757 | molecular_function | glycosyltransferase activity |
A | 0047975 | molecular_function | guanosine phosphorylase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
B | 0009116 | biological_process | nucleoside metabolic process |
B | 0016757 | molecular_function | glycosyltransferase activity |
B | 0047975 | molecular_function | guanosine phosphorylase activity |
C | 0003824 | molecular_function | catalytic activity |
C | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0006139 | biological_process | nucleobase-containing compound metabolic process |
C | 0009116 | biological_process | nucleoside metabolic process |
C | 0016757 | molecular_function | glycosyltransferase activity |
C | 0047975 | molecular_function | guanosine phosphorylase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE NOS A 301 |
Chain | Residue |
A | TYR90 |
A | THR244 |
A | ASN245 |
A | HIS259 |
A | VAL262 |
A | HOH340 |
A | HOH424 |
A | SO4706 |
B | PHE161 |
A | ALA118 |
A | ALA119 |
A | GLY120 |
A | TYR202 |
A | GLU203 |
A | VAL219 |
A | GLY220 |
A | MET221 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 A 706 |
Chain | Residue |
A | ARG86 |
A | HIS88 |
A | ASN117 |
A | ALA118 |
A | SER222 |
A | NOS301 |
A | HOH421 |
A | HOH424 |
site_id | AC3 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE NOS B 301 |
Chain | Residue |
B | TYR90 |
B | ALA118 |
B | ALA119 |
B | GLY120 |
B | TYR202 |
B | GLU203 |
B | VAL219 |
B | GLY220 |
B | MET221 |
B | THR244 |
B | ASN245 |
B | HIS259 |
B | VAL262 |
B | HOH314 |
B | HOH320 |
C | PHE161 |
site_id | AC4 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE NOS C 301 |
Chain | Residue |
C | TYR90 |
C | ALA118 |
C | ALA119 |
C | GLY120 |
C | TYR202 |
C | GLU203 |
C | VAL219 |
C | GLY220 |
C | MET221 |
C | THR244 |
C | ASN245 |
C | HIS259 |
C | VAL262 |
C | HOH295 |
C | HOH333 |
C | SO4706 |
site_id | AC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 C 706 |
Chain | Residue |
C | ARG86 |
C | HIS88 |
C | ASN117 |
C | ALA118 |
C | SER222 |
C | HOH295 |
C | NOS301 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ula |
Chain | Residue | Details |
A | ASN245 | |
A | HIS88 | |
A | GLU91 |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ula |
Chain | Residue | Details |
B | ASN245 | |
B | HIS88 | |
B | GLU91 |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ula |
Chain | Residue | Details |
C | ASN245 | |
C | HIS88 | |
C | GLU91 |