Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016833 | molecular_function | oxo-acid-lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016833 | molecular_function | oxo-acid-lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016833 | molecular_function | oxo-acid-lyase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016833 | molecular_function | oxo-acid-lyase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016833 | molecular_function | oxo-acid-lyase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016833 | molecular_function | oxo-acid-lyase activity |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0016833 | molecular_function | oxo-acid-lyase activity |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0003824 | molecular_function | catalytic activity |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0016833 | molecular_function | oxo-acid-lyase activity |
| H | 0046872 | molecular_function | metal ion binding |
| I | 0003824 | molecular_function | catalytic activity |
| I | 0016787 | molecular_function | hydrolase activity |
| I | 0016833 | molecular_function | oxo-acid-lyase activity |
| I | 0046872 | molecular_function | metal ion binding |
| J | 0003824 | molecular_function | catalytic activity |
| J | 0016787 | molecular_function | hydrolase activity |
| J | 0016833 | molecular_function | oxo-acid-lyase activity |
| J | 0046872 | molecular_function | metal ion binding |
| K | 0003824 | molecular_function | catalytic activity |
| K | 0016787 | molecular_function | hydrolase activity |
| K | 0016833 | molecular_function | oxo-acid-lyase activity |
| K | 0046872 | molecular_function | metal ion binding |
| L | 0003824 | molecular_function | catalytic activity |
| L | 0016787 | molecular_function | hydrolase activity |
| L | 0016833 | molecular_function | oxo-acid-lyase activity |
| L | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 401 |
| Chain | Residue |
| A | ASP87 |
| A | ASP89 |
| A | HOH765 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 401 |
| Chain | Residue |
| B | ASP87 |
| B | ASP89 |
| B | HOH370 |
| B | HOH902 |
| B | HOH903 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG C 401 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 401 |
| Chain | Residue |
| D | ASP87 |
| D | ASP89 |
| D | HOH495 |
| D | HOH868 |
| D | HOH905 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG E 401 |
| Chain | Residue |
| E | ASP87 |
| E | ASP89 |
| E | HOH760 |
| E | HOH869 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG F 401 |
| Chain | Residue |
| F | ASP59 |
| F | ASP87 |
| F | ASP89 |
| F | HOH840 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG G 401 |
| Chain | Residue |
| G | ASP87 |
| G | ASP89 |
| G | HOH598 |
| G | HOH762 |
| G | HOH918 |
| G | HOH1071 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG H 401 |
| Chain | Residue |
| H | ASP59 |
| H | ASP87 |
| H | ASP89 |
| H | HOH873 |
| H | HOH884 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG I 401 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG J 401 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG K 401 |
| Chain | Residue |
| K | ASP59 |
| K | ASP87 |
| K | ASP89 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG L 401 |
| Chain | Residue |
| L | ASP59 |
| L | ASP87 |
| L | ASP89 |
| L | HOH304 |
Functional Information from PROSITE/UniProt
| site_id | PS00161 |
| Number of Residues | 6 |
| Details | ISOCITRATE_LYASE Isocitrate lyase signature. KRCGHL |
| Chain | Residue | Details |
| A | LYS122-LEU127 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| A | HIS114 | |
| A | ARG161 | |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| J | HIS114 | |
| J | ARG161 | |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| K | HIS114 | |
| K | ARG161 | |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| L | HIS114 | |
| L | ARG161 | |
| L | CYS124 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| B | HIS114 | |
| B | ARG161 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| C | HIS114 | |
| C | ARG161 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| D | HIS114 | |
| D | ARG161 | |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| E | HIS114 | |
| E | ARG161 | |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| F | HIS114 | |
| F | ARG161 | |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| G | HIS114 | |
| G | ARG161 | |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| H | HIS114 | |
| H | ARG161 | |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1f8m |
| Chain | Residue | Details |
| I | HIS114 | |
| I | ARG161 | |
