3F5N

Structure of native human neuroserpin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004867	molecular_function	serine-type endopeptidase inhibitor activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0007417	biological_process	central nervous system development
A	0007422	biological_process	peripheral nervous system development
A	0010976	biological_process	positive regulation of neuron projection development
A	0030414	molecular_function	peptidase inhibitor activity
A	0031410	cellular_component	cytoplasmic vesicle
A	0034774	cellular_component	secretory granule lumen
A	0043025	cellular_component	neuronal cell body
A	0043204	cellular_component	perikaryon
A	0060205	cellular_component	cytoplasmic vesicle lumen
A	0070062	cellular_component	extracellular exosome
B	0004867	molecular_function	serine-type endopeptidase inhibitor activity
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0007417	biological_process	central nervous system development
B	0007422	biological_process	peripheral nervous system development
B	0010976	biological_process	positive regulation of neuron projection development
B	0030414	molecular_function	peptidase inhibitor activity
B	0031410	cellular_component	cytoplasmic vesicle
B	0034774	cellular_component	secretory granule lumen
B	0043025	cellular_component	neuronal cell body
B	0043204	cellular_component	perikaryon
B	0060205	cellular_component	cytoplasmic vesicle lumen
B	0070062	cellular_component	extracellular exosome
C	0004867	molecular_function	serine-type endopeptidase inhibitor activity
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0007417	biological_process	central nervous system development
C	0007422	biological_process	peripheral nervous system development
C	0010976	biological_process	positive regulation of neuron projection development
C	0030414	molecular_function	peptidase inhibitor activity
C	0031410	cellular_component	cytoplasmic vesicle
C	0034774	cellular_component	secretory granule lumen
C	0043025	cellular_component	neuronal cell body
C	0043204	cellular_component	perikaryon
C	0060205	cellular_component	cytoplasmic vesicle lumen
C	0070062	cellular_component	extracellular exosome
D	0004867	molecular_function	serine-type endopeptidase inhibitor activity
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0007417	biological_process	central nervous system development
D	0007422	biological_process	peripheral nervous system development
D	0010976	biological_process	positive regulation of neuron projection development
D	0030414	molecular_function	peptidase inhibitor activity
D	0031410	cellular_component	cytoplasmic vesicle
D	0034774	cellular_component	secretory granule lumen
D	0043025	cellular_component	neuronal cell body
D	0043204	cellular_component	perikaryon
D	0060205	cellular_component	cytoplasmic vesicle lumen
D	0070062	cellular_component	extracellular exosome
E	0004867	molecular_function	serine-type endopeptidase inhibitor activity
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0007417	biological_process	central nervous system development
E	0007422	biological_process	peripheral nervous system development
E	0010976	biological_process	positive regulation of neuron projection development
E	0030414	molecular_function	peptidase inhibitor activity
E	0031410	cellular_component	cytoplasmic vesicle
E	0034774	cellular_component	secretory granule lumen
E	0043025	cellular_component	neuronal cell body
E	0043204	cellular_component	perikaryon
E	0060205	cellular_component	cytoplasmic vesicle lumen
E	0070062	cellular_component	extracellular exosome

Functional Information from PROSITE/UniProt

site_id	PS00284
Number of Residues	11
Details	SERPIN Serpins signature. VIVDHPFFFlI

Chain	Residue	Details
A	VAL370-ILE380

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Site: {"description":"Reactive bond","evidences":[{"source":"PubMed","id":"19265707","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19285087","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	11
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (Xyl...) (chondroitin sulfate) serine","evidences":[{"source":"PubMed","id":"25326458","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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