3ES6
Crystal structure of the novel complex formed between Zinc 2-glycoprotein (ZAG) and Prolactin inducible protein (PIP) from human seminal plasma
Replaces: 2ICNFunctional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001580 | biological_process | detection of chemical stimulus involved in sensory perception of bitter taste |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005634 | cellular_component | nucleus |
| A | 0006955 | biological_process | immune response |
| A | 0007155 | biological_process | cell adhesion |
| A | 0008285 | biological_process | negative regulation of cell population proliferation |
| A | 0008320 | molecular_function | protein transmembrane transporter activity |
| A | 0009897 | cellular_component | external side of plasma membrane |
| A | 0062023 | cellular_component | collagen-containing extracellular matrix |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0071806 | biological_process | protein transmembrane transport |
| B | 0001580 | biological_process | detection of chemical stimulus involved in sensory perception of bitter taste |
| B | 0002682 | biological_process | regulation of immune system process |
| B | 0003779 | molecular_function | actin binding |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005634 | cellular_component | nucleus |
| B | 0006508 | biological_process | proteolysis |
| B | 0010628 | biological_process | positive regulation of gene expression |
| B | 0019864 | molecular_function | IgG binding |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0070233 | biological_process | negative regulation of T cell apoptotic process |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCHVQH |
| Chain | Residue | Details |
| A | TYR258-HIS264 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:2013294, ECO:0000269|PubMed:25946035 |
| Chain | Residue | Details |
| B | GLN1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:18780401, ECO:0000269|PubMed:18930737, ECO:0000269|PubMed:2013294 |
| Chain | Residue | Details |
| B | ASN77 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:18780401, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | HIS95 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:10206894, ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:15477100, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:18780401, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:22171320 |
| Chain | Residue | Details |
| A | SER111 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10206894, ECO:0000269|PubMed:15477100, ECO:0000269|PubMed:18930737 |
| Chain | Residue | Details |
| A | TYR242 |
