Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051596 | biological_process | methylglyoxal catabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051596 | biological_process | methylglyoxal catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 333 |
| Chain | Residue |
| A | HIS155 |
| A | HIS159 |
| A | HOH765 |
| A | HOH767 |
| A | HOH770 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 334 |
| Chain | Residue |
| A | HIS138 |
| A | SER168 |
| A | GLN193 |
| A | CAC337 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 335 |
| Chain | Residue |
| A | SER222 |
| A | LEU224 |
| A | GLY226 |
| A | HOH572 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 336 |
| Chain | Residue |
| A | HIS155 |
| A | HIS159 |
| A | HOH575 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CAC A 337 |
| Chain | Residue |
| A | TRP33 |
| A | TYR66 |
| A | HIS138 |
| A | ASN169 |
| A | PHE221 |
| A | NA334 |
| A | EDO342 |
| A | HOH771 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 338 |
| Chain | Residue |
| A | LEU269 |
| A | ARG272 |
| A | GLU320 |
| A | EDO339 |
| A | HOH430 |
| B | ASN169 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 339 |
| Chain | Residue |
| A | ARG272 |
| A | EDO338 |
| A | HOH443 |
| B | TYR170 |
| B | VAL203 |
| B | HOH782 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 340 |
| Chain | Residue |
| A | ALA172 |
| A | ASP173 |
| A | ARG176 |
| A | HOH630 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 341 |
| Chain | Residue |
| A | ALA257 |
| A | ASP258 |
| A | GLU261 |
| A | ARG331 |
| A | PHE332 |
| B | TYR15 |
| B | LYS24 |
| B | HOH772 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 342 |
| Chain | Residue |
| A | ASN65 |
| A | TYR66 |
| A | TYR100 |
| A | HIS138 |
| A | CAC337 |
| A | HOH686 |
| A | HOH699 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 343 |
| Chain | Residue |
| A | ARG17 |
| A | TRP110 |
| A | ASP141 |
| A | PRO142 |
| A | GLU143 |
| A | HOH395 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 344 |
| Chain | Residue |
| A | THR40 |
| A | ARG41 |
| A | HOH383 |
| B | ARG41 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 345 |
| Chain | Residue |
| A | CYS75 |
| A | ASN76 |
| A | ARG79 |
| A | HOH480 |
| B | ARG79 |
| B | HOH733 |
| B | HOH827 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 346 |
| Chain | Residue |
| A | ARG9 |
| A | GLU91 |
| A | TRP103 |
| A | ASP104 |
| A | HOH781 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 333 |
| Chain | Residue |
| B | HIS155 |
| B | HOH895 |
| B | HOH897 |
| B | HOH901 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 334 |
| Chain | Residue |
| B | LYS97 |
| B | HIS138 |
| B | SER168 |
| B | GLN193 |
| B | CAC338 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 335 |
| Chain | Residue |
| B | SER222 |
| B | LEU224 |
| B | GLY226 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 336 |
| Chain | Residue |
| A | SER317 |
| A | HOH430 |
| B | LYS195 |
| B | HOH665 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 337 |
| Chain | Residue |
| B | HIS155 |
| B | HIS159 |
| B | HOH637 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CAC B 338 |
| Chain | Residue |
| B | ASN169 |
| B | PHE221 |
| B | NA334 |
| B | TRP33 |
| B | TYR66 |
| B | HIS138 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 339 |
| Chain | Residue |
| B | ALA172 |
| B | ASP173 |
| B | ARG176 |
| B | HOH771 |
| B | HOH852 |
| site_id | CC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO B 340 |
| Chain | Residue |
| A | ALA326 |
| B | TYR100 |
| B | THR101 |
| B | ARG139 |
| B | HOH550 |
| B | HOH577 |
| B | HOH638 |
| B | HOH693 |
| B | HOH884 |
| site_id | CC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 341 |
| Chain | Residue |
| A | ARG41 |
| B | THR39 |
| B | THR40 |
| B | ARG41 |
| B | ASN44 |
| B | HOH657 |
| B | HOH892 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 342 |
| Chain | Residue |
| A | ARG272 |
| A | ARG273 |
| A | ASN313 |
| B | GLU200 |
| B | TRP202 |
| B | HOH579 |
| B | HOH782 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| A | LYS97 | |
| A | ASP61 | |
| A | HIS138 | |
| A | TYR66 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| B | LYS97 | |
| B | ASP61 | |
| B | HIS138 | |
| B | TYR66 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| A | LYS97 | |
| A | TYR66 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| B | LYS97 | |
| B | TYR66 | |
