Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006508 | biological_process | proteolysis |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0070012 | molecular_function | oligopeptidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE X99 A 711 |
Chain | Residue |
A | PHE173 |
A | CYS255 |
A | TYR473 |
A | PHE476 |
A | SER554 |
A | VAL580 |
A | TRP595 |
A | TYR599 |
A | ARG643 |
Functional Information from PROSITE/UniProt
site_id | PS00708 |
Number of Residues | 31 |
Details | PRO_ENDOPEP_SER Prolyl endopeptidase family serine active site. DfqcAaeyLikegytspkrltinGgSnGGLL |
Chain | Residue | Details |
A | ASP529-LEU559 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | SER554 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | ASP641 | |
Chain | Residue | Details |
A | HIS680 | |
Chain | Residue | Details |
A | LYS157 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1pfq |
Chain | Residue | Details |
A | ASP641 | |
A | SER554 | |
A | HIS680 | |
site_id | MCSA1 |
Number of Residues | 4 |
Details | M-CSA 901 |
Chain | Residue | Details |
A | TYR473 | electrostatic stabiliser |
A | SER554 | covalent catalysis, proton shuttle (general acid/base) |
A | ASP641 | electrostatic stabiliser, modifies pKa |
A | HIS680 | proton shuttle (general acid/base) |