3EQ3
Model of tRNA(Trp)-EF-Tu in the ribosomal pre-accommodated state revealed by cryo-EM
Functional Information from GO Data
Chain | GOid | namespace | contents |
I | 0000027 | biological_process | ribosomal large subunit assembly |
I | 0002181 | biological_process | cytoplasmic translation |
I | 0003735 | molecular_function | structural constituent of ribosome |
I | 0005515 | molecular_function | protein binding |
I | 0005737 | cellular_component | cytoplasm |
I | 0005829 | cellular_component | cytosol |
I | 0005840 | cellular_component | ribosome |
I | 0006412 | biological_process | translation |
I | 0006415 | biological_process | translational termination |
I | 0015968 | biological_process | stringent response |
I | 0019843 | molecular_function | rRNA binding |
I | 0022625 | cellular_component | cytosolic large ribosomal subunit |
I | 0070180 | molecular_function | large ribosomal subunit rRNA binding |
I | 1990904 | cellular_component | ribonucleoprotein complex |
L | 0000049 | molecular_function | tRNA binding |
L | 0000372 | biological_process | Group I intron splicing |
L | 0002181 | biological_process | cytoplasmic translation |
L | 0003735 | molecular_function | structural constituent of ribosome |
L | 0005515 | molecular_function | protein binding |
L | 0005737 | cellular_component | cytoplasm |
L | 0005829 | cellular_component | cytosol |
L | 0005840 | cellular_component | ribosome |
L | 0006412 | biological_process | translation |
L | 0015935 | cellular_component | small ribosomal subunit |
L | 0019843 | molecular_function | rRNA binding |
L | 0022627 | cellular_component | cytosolic small ribosomal subunit |
L | 0033120 | biological_process | positive regulation of RNA splicing |
L | 0034336 | molecular_function | misfolded RNA binding |
L | 0034337 | biological_process | RNA folding |
L | 0046677 | biological_process | response to antibiotic |
L | 1990145 | biological_process | maintenance of translational fidelity |
L | 1990904 | cellular_component | ribonucleoprotein complex |
X | 0003746 | molecular_function | translation elongation factor activity |
X | 0003924 | molecular_function | GTPase activity |
X | 0005525 | molecular_function | GTP binding |
X | 0006414 | biological_process | translational elongation |
Functional Information from PROSITE/UniProt
site_id | PS00055 |
Number of Residues | 8 |
Details | RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR |
Chain | Residue | Details |
L | LYS42-ARG49 |
site_id | PS00301 |
Number of Residues | 16 |
Details | G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DNapeEKaRGITIntS |
Chain | Residue | Details |
X | ASP50-SER65 |
site_id | PS00359 |
Number of Residues | 16 |
Details | RIBOSOMAL_L11 Ribosomal protein L11 signature. RsIeGTarSMGlVVeD |
Chain | Residue | Details |
I | ARG126-ASP141 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | MOD_RES: N,N,N-trimethylalanine => ECO:0000269|PubMed:7004866 |
Chain | Residue | Details |
I | ALA1 | |
X | ASP80 | |
X | ASN135 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | MOD_RES: N6,N6,N6-trimethyllysine => ECO:0000269|PubMed:7004866 |
Chain | Residue | Details |
I | LYS3 | |
I | LYS39 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | MOD_RES: N6-succinyllysine => ECO:0000269|PubMed:21151122 |
Chain | Residue | Details |
I | LYS71 | |
I | LYS80 | |
X | LYS248 | |
X | LYS252 | |
X | LYS294 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:2022614, ECO:0000269|PubMed:389663, ECO:0000269|PubMed:6997043, ECO:0000269|PubMed:7021545 |
Chain | Residue | Details |
X | LYS56 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:21151122 |
Chain | Residue | Details |
X | LYS313 |
site_id | SWS_FT_FI6 |
Number of Residues | 1 |
Details | MOD_RES: Phosphothreonine => ECO:0000305|PubMed:19150849, ECO:0000305|PubMed:24141193, ECO:0000305|PubMed:8416965 |
Chain | Residue | Details |
X | THR382 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ksj |
Chain | Residue | Details |
X | ASP21 |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ksj |
Chain | Residue | Details |
X | HIS84 |