Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3EOO

2.9A crystal structure of methyl-isocitrate lyase from Burkholderia pseudomallei

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
A	0046421	molecular_function	methylisocitrate lyase activity
B	0003824	molecular_function	catalytic activity
B	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
B	0046421	molecular_function	methylisocitrate lyase activity
C	0003824	molecular_function	catalytic activity
C	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
C	0046421	molecular_function	methylisocitrate lyase activity
D	0003824	molecular_function	catalytic activity
D	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
D	0046421	molecular_function	methylisocitrate lyase activity
E	0003824	molecular_function	catalytic activity
E	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
E	0046421	molecular_function	methylisocitrate lyase activity
F	0003824	molecular_function	catalytic activity
F	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
F	0046421	molecular_function	methylisocitrate lyase activity
G	0003824	molecular_function	catalytic activity
G	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
G	0046421	molecular_function	methylisocitrate lyase activity
H	0003824	molecular_function	catalytic activity
H	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
H	0046421	molecular_function	methylisocitrate lyase activity
I	0003824	molecular_function	catalytic activity
I	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
I	0046421	molecular_function	methylisocitrate lyase activity
J	0003824	molecular_function	catalytic activity
J	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
J	0046421	molecular_function	methylisocitrate lyase activity
K	0003824	molecular_function	catalytic activity
K	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
K	0046421	molecular_function	methylisocitrate lyase activity
L	0003824	molecular_function	catalytic activity
L	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
L	0046421	molecular_function	methylisocitrate lyase activity
M	0003824	molecular_function	catalytic activity
M	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
M	0046421	molecular_function	methylisocitrate lyase activity
N	0003824	molecular_function	catalytic activity
N	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
N	0046421	molecular_function	methylisocitrate lyase activity
O	0003824	molecular_function	catalytic activity
O	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
O	0046421	molecular_function	methylisocitrate lyase activity
P	0003824	molecular_function	catalytic activity
P	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
P	0046421	molecular_function	methylisocitrate lyase activity

Functional Information from PROSITE/UniProt

site_id	PS00161
Number of Residues	6
Details	ISOCITRATE_LYASE Isocitrate lyase signature. KRCGHR

Chain	Residue	Details
A	LYS123-ARG128

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
A	ARG160
A	HIS115
A	CYS125

site_id	CSA10
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
J	ARG160
J	HIS115
J	CYS125

site_id	CSA11
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
K	ARG160
K	HIS115
K	CYS125

site_id	CSA12
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
L	ARG160
L	HIS115
L	CYS125

site_id	CSA13
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
M	ARG160
M	HIS115
M	CYS125

site_id	CSA14
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
N	ARG160
N	HIS115
N	CYS125

site_id	CSA15
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
O	ARG160
O	HIS115
O	CYS125

site_id	CSA16
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
P	ARG160
P	HIS115
P	CYS125

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
B	ARG160
B	HIS115
B	CYS125

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
C	ARG160
C	HIS115
C	CYS125

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
D	ARG160
D	HIS115
D	CYS125

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
E	ARG160
E	HIS115
E	CYS125

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
F	ARG160
F	HIS115
F	CYS125

site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
G	ARG160
G	HIS115
G	CYS125

site_id	CSA8
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
H	ARG160
H	HIS115
H	CYS125

site_id	CSA9
Number of Residues	3
Details	Annotated By Reference To The Literature 1f8m

Chain	Residue	Details
I	ARG160
I	HIS115
I	CYS125

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)