3EO8
Crystal structure of BluB-like flavoprotein (YP_001089088.1) from CLOSTRIDIUM DIFFICILE 630 at 1.74 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0006570 | biological_process | tyrosine metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042403 | biological_process | thyroid hormone metabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0006570 | biological_process | tyrosine metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042403 | biological_process | thyroid hormone metabolic process |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0006570 | biological_process | tyrosine metabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0042403 | biological_process | thyroid hormone metabolic process |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0006570 | biological_process | tyrosine metabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0042403 | biological_process | thyroid hormone metabolic process |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0006570 | biological_process | tyrosine metabolic process |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0042403 | biological_process | thyroid hormone metabolic process |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0006570 | biological_process | tyrosine metabolic process |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0042403 | biological_process | thyroid hormone metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE FMN A 500 |
| Chain | Residue |
| A | ARG10 |
| A | THR163 |
| A | SER164 |
| A | SER204 |
| A | PRO205 |
| A | LYS207 |
| A | HOH782 |
| A | HOH790 |
| A | HOH810 |
| B | PRO37 |
| B | SER38 |
| A | GLN11 |
| B | GLY39 |
| B | ASN41 |
| B | PRO136 |
| B | ACT501 |
| A | SER12 |
| A | ARG14 |
| A | PHE92 |
| A | PHE95 |
| A | CYS160 |
| A | TRP161 |
| A | LEU162 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 501 |
| Chain | Residue |
| A | GLY39 |
| A | LYS40 |
| A | HOH675 |
| A | HOH712 |
| B | PHE88 |
| B | FMN500 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 502 |
| Chain | Residue |
| A | LYS66 |
| A | TYR167 |
| A | ALA169 |
| A | ASP170 |
| A | GLU171 |
| B | LYS130 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 503 |
| Chain | Residue |
| A | SER113 |
| A | HOH675 |
| B | THR163 |
| B | SER164 |
| site_id | AC5 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE FMN B 500 |
| Chain | Residue |
| A | PRO37 |
| A | SER38 |
| A | GLY39 |
| A | ASN41 |
| A | PRO136 |
| A | ACT501 |
| B | ARG10 |
| B | GLN11 |
| B | SER12 |
| B | ARG14 |
| B | PHE92 |
| B | PHE95 |
| B | CYS160 |
| B | TRP161 |
| B | LEU162 |
| B | THR163 |
| B | SER164 |
| B | SER204 |
| B | PRO205 |
| B | LYS207 |
| B | HOH796 |
| B | HOH816 |
| B | HOH818 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 501 |
| Chain | Residue |
| A | PHE88 |
| A | FMN500 |
| B | LYS40 |
| B | HOH747 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 502 |
| Chain | Residue |
| B | LYS66 |
| B | TYR167 |
| B | ALA169 |
| B | ASP170 |
| B | GLU171 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 503 |
| Chain | Residue |
| A | THR163 |
| A | SER164 |
| B | PRO112 |
| B | SER113 |
| B | HOH564 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 504 |
| Chain | Residue |
| B | ASP80 |
| B | LYS81 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 505 |
| Chain | Residue |
| B | PHE182 |
| B | GLU183 |
| B | LYS184 |
| B | TYR187 |
| B | HOH837 |
| site_id | BC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE FMN C 500 |
| Chain | Residue |
| C | HOH793 |
| D | PRO37 |
| D | SER38 |
| D | GLY39 |
| D | ASN41 |
| D | PRO136 |
| D | SER140 |
| D | ACT501 |
| C | ARG10 |
| C | GLN11 |
| C | SER12 |
| C | ARG14 |
| C | PHE92 |
| C | PHE95 |
| C | CYS160 |
| C | TRP161 |
| C | LEU162 |
| C | THR163 |
| C | SER164 |
| C | SER204 |
| C | PRO205 |
| C | LYS207 |
| C | HOH770 |
| C | HOH783 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT C 501 |
| Chain | Residue |
| C | LYS40 |
| C | HOH596 |
| C | HOH754 |
| D | PHE88 |
| D | FMN500 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 502 |
| Chain | Residue |
| C | TYR110 |
| C | SER113 |
| C | HOH754 |
| D | THR163 |
| D | SER164 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 503 |
| Chain | Residue |
| C | GLU179 |
| C | THR180 |
| C | GLY181 |
| C | HOH583 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 504 |
| Chain | Residue |
| C | HIS46 |
| C | GLU183 |
| C | LYS184 |
| C | TYR187 |
| C | HOH524 |
| D | GLU212 |
| D | HOH547 |
| site_id | BC7 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE FMN D 500 |
| Chain | Residue |
| C | PRO37 |
| C | SER38 |
| C | GLY39 |
| C | ASN41 |
| C | PRO136 |
| C | ACT501 |
| D | ARG10 |
| D | GLN11 |
| D | SER12 |
| D | ARG14 |
| D | PHE92 |
| D | PHE95 |
| D | CYS160 |
| D | TRP161 |
| D | LEU162 |
| D | THR163 |
| D | SER164 |
| D | SER204 |
| D | PRO205 |
| D | LYS207 |
| D | HOH778 |
| D | HOH787 |
| D | HOH790 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT D 501 |
| Chain | Residue |
| C | FMN500 |
| D | LYS40 |
| D | HOH565 |
| D | HOH682 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT D 502 |
| Chain | Residue |
| D | LYS66 |
| D | TYR167 |
| D | ALA169 |
| D | ASP170 |
| D | GLU171 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 503 |
| Chain | Residue |
| C | THR163 |
| C | SER164 |
| D | SER113 |
| D | HOH572 |
| site_id | CC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL D 504 |
| Chain | Residue |
| C | PHE216 |
| C | HOH811 |
| D | ASP23 |
| D | LEU27 |
| E | HOH1786 |
| F | ASP80 |
| F | LYS81 |
| F | ARG84 |
| site_id | CC3 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE FMN E 500 |
| Chain | Residue |
| E | ARG10 |
| E | GLN11 |
| E | SER12 |
| E | ARG14 |
| E | PHE92 |
| E | PHE95 |
| E | CYS160 |
| E | TRP161 |
| E | LEU162 |
| E | THR163 |
| E | SER164 |
| E | SER204 |
| E | PRO205 |
| E | LYS207 |
| E | HOH1921 |
| E | HOH1926 |
| E | HOH1961 |
| F | PRO37 |
| F | SER38 |
| F | GLY39 |
| F | ASN41 |
| F | PRO136 |
| F | SER140 |
| F | ACT501 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT E 501 |
| Chain | Residue |
| E | GLY39 |
| E | LYS40 |
| E | HOH1834 |
| E | HOH1913 |
| F | PHE88 |
| F | FMN500 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT E 502 |
| Chain | Residue |
| E | LYS66 |
| E | TYR167 |
| E | ALA169 |
| E | ASP170 |
| E | GLU171 |
| F | LYS130 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT E 503 |
| Chain | Residue |
| E | TYR116 |
| E | HOH1786 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL E 504 |
| Chain | Residue |
| E | SER113 |
| E | HOH1913 |
| F | THR163 |
| F | SER164 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL E 505 |
| Chain | Residue |
| E | LYS66 |
| E | HOH1747 |
| E | HOH1780 |
| E | HOH1953 |
| F | LEU118 |
| site_id | CC9 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE FMN F 500 |
| Chain | Residue |
| E | PRO37 |
| E | SER38 |
| E | GLY39 |
| E | ASN41 |
| E | PRO136 |
| E | SER140 |
| E | ACT501 |
| F | ARG10 |
| F | GLN11 |
| F | SER12 |
| F | ARG14 |
| F | PHE92 |
| F | PHE95 |
| F | CYS160 |
| F | TRP161 |
| F | LEU162 |
| F | THR163 |
| F | SER164 |
| F | SER204 |
| F | PRO205 |
| F | LYS207 |
| F | HOH507 |
| F | HOH544 |
| F | HOH633 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT F 501 |
| Chain | Residue |
| E | PHE88 |
| E | FMN500 |
| F | GLY39 |
| F | LYS40 |
| F | HOH1075 |
| F | HOH1225 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT F 502 |
| Chain | Residue |
| E | LYS130 |
| F | LYS66 |
| F | TYR167 |
| F | ALA169 |
| F | ASP170 |
| F | GLU171 |
| site_id | DC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL F 503 |
| Chain | Residue |
| E | THR163 |
| E | SER164 |
| F | PRO112 |
| F | SER113 |
| F | HOH1075 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL F 504 |
| Chain | Residue |
| A | GLY181 |
| A | HOH748 |
| A | HOH804 |
| F | HOH1025 |
| F | HOH1225 |
