3EMD

Wesselsbron virus Methyltransferase in complex with Sinefungin and 7MeGpppA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004386	molecular_function	helicase activity
A	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
A	0004483	molecular_function	methyltransferase cap1 activity
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0008168	molecular_function	methyltransferase activity
A	0032259	biological_process	methylation
A	0106005	biological_process	RNA 5'-cap (guanine-N7)-methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE SFG A 293

Chain	Residue
A	SER56
A	GLU111
A	SER130
A	ASN131
A	VAL132
A	PHE133
A	ASP146
A	ILE147
A	SO4404
A	HOH440
A	HOH500
A	GLY58
A	HOH612
A	HOH681
A	GLY81
A	CYS82
A	GLY83
A	GLY86
A	TRP87
A	THR104
A	LEU105

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site_id	AC2
Number of Residues	21
Details	BINDING SITE FOR RESIDUE GTA A 401

Chain	Residue
A	LYS13
A	LEU16
A	ASN17
A	LEU19
A	LYS21
A	PHE24
A	SER150
A	SER151
A	SER152
A	GLU193
A	ARG197
A	SER215
A	HOH462
A	HOH486
A	HOH496
A	HOH598
A	HOH637
A	HOH659
A	HOH669
A	HOH670
A	HOH680

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 402

Chain	Residue
A	ARG37
A	ARG41
A	ARG57
A	ARG84

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 403

Chain	Residue
A	HIS231
A	ASN234
A	ARG238
A	HOH610

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site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 404

Chain	Residue
A	GLY58
A	LYS61
A	SFG293
A	HOH466
A	HOH536
A	HOH613
A	HOH657

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