3ELW

Wesselsbron virus Methyltransferase in complex with AdoMet and GpppG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
A	0004483	molecular_function	mRNA (nucleoside-2'-O-)-methyltransferase activity
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0008168	molecular_function	methyltransferase activity
A	0032259	biological_process	methylation
A	0106005	biological_process	RNA 5'-cap (guanine-N7)-methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 293

Chain	Residue
A	HIS231
A	ASN234
A	ARG238

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 294

Chain	Residue
A	ARG37
A	ARG41
A	ARG57
A	ARG84
A	GP34634

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 295

Chain	Residue
A	HIS115
A	TRP121
A	VAL124
A	HOH4687
A	TYR89

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 296

Chain	Residue
A	ARG160
A	HOH4867

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site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 297

Chain	Residue
A	LYS61
A	ARG213
A	HOH4933
A	HOH4936
A	HOH4938
A	HOH4944

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site_id	AC6
Number of Residues	21
Details	BINDING SITE FOR RESIDUE SAM A4633

Chain	Residue
A	SER56
A	GLY58
A	GLY81
A	CYS82
A	GLY83
A	GLY85
A	GLY86
A	TRP87
A	THR104
A	LEU105
A	HIS110
A	SER130
A	ASN131
A	VAL132
A	PHE133
A	ASP146
A	HOH4661
A	HOH4665
A	HOH4666
A	HOH4791
A	HOH4932

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site_id	AC7
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GP3 A4634

Chain	Residue
A	LYS13
A	LEU16
A	LEU19
A	PHE24
A	LYS28
A	ARG57
A	SER151
A	SER152
A	ARG197
A	LEU200
A	ARG201
A	ARG213
A	SER215
A	SO4294
A	HOH4697
A	HOH4719
A	HOH4731
A	HOH4789
A	HOH4818
A	HOH4820
A	HOH4847
A	HOH4906
A	HOH4928

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