Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 100 |
| Chain | Residue |
| A | PRO1 |
| A | ARG57 |
| A | HIS69 |
| A | HOH203 |
| A | HOH215 |
| B | HOH171 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 101 |
| Chain | Residue |
| A | LYS7 |
| A | ARG8 |
| A | HOH144 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 102 |
| Chain | Residue |
| A | HOH132 |
| A | HOH463 |
| B | ARG14 |
| B | ILE15 |
| B | GLY16 |
| B | GLY17 |
| B | HOH116 |
| B | HOH129 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 103 |
| Chain | Residue |
| A | GLU21 |
| A | ALA22 |
| A | THR82 |
| A | ASN83 |
| A | ACT104 |
| A | HOH200 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 104 |
| Chain | Residue |
| A | LYS20 |
| A | GLU21 |
| A | ACT103 |
| A | HOH247 |
| A | HOH254 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 105 |
| Chain | Residue |
| A | MET36 |
| A | ASN37 |
| B | PRO39 |
| B | GLY40 |
| B | HOH302 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 1UN B 201 |
| Chain | Residue |
| A | ASP25 |
| A | GLY27 |
| A | ASP30 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | PRO81 |
| A | THR82 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | VAL32 |
| B | GLY49 |
| B | ILE50 |
| B | THR80 |
| B | PRO81 |
| B | HOH125 |
| B | HOH156 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT B 100 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 101 |
| Chain | Residue |
| A | LYS55 |
| B | GLN2 |
| B | ARG14 |
| B | LYS70 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 102 |
| Chain | Residue |
| A | PRO39 |
| A | GLY40 |
| B | MET36 |
| B | ASN37 |
| B | HOH205 |
| B | HOH317 |
| B | HOH318 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 103 |
| Chain | Residue |
| B | GLU21 |
| B | ARG41 |
| B | ASN83 |
| B | HOH135 |
| B | HOH370 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 104 |
| Chain | Residue |
| B | GLY73 |
| B | THR74 |
| B | ASN88 |
| B | HOH114 |
| B | HOH155 |
| B | HOH174 |
| B | HOH396 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| B | ASP25 | |
| B | THR26 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| B | ASP25 | |
