3EJD

Crystal Structure of P450BioI in complex with hexadec-9Z-enoic acid ligated Acyl Carrier Protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000035	molecular_function	acyl binding
A	0000036	molecular_function	acyl carrier activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0008289	molecular_function	lipid binding
A	0008610	biological_process	lipid biosynthetic process
A	0009245	biological_process	lipid A biosynthetic process
A	0009410	biological_process	response to xenobiotic stimulus
A	0031177	molecular_function	phosphopantetheine binding
B	0004497	molecular_function	monooxygenase activity
B	0005506	molecular_function	iron ion binding
B	0006707	biological_process	cholesterol catabolic process
B	0008395	molecular_function	steroid hydroxylase activity
B	0009102	biological_process	biotin biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
B	0020037	molecular_function	heme binding
B	0036199	molecular_function	cholest-4-en-3-one 26-monooxygenase activity
B	0046872	molecular_function	metal ion binding
C	0000035	molecular_function	acyl binding
C	0000036	molecular_function	acyl carrier activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006633	biological_process	fatty acid biosynthetic process
C	0008289	molecular_function	lipid binding
C	0008610	biological_process	lipid biosynthetic process
C	0009245	biological_process	lipid A biosynthetic process
C	0009410	biological_process	response to xenobiotic stimulus
C	0031177	molecular_function	phosphopantetheine binding
D	0004497	molecular_function	monooxygenase activity
D	0005506	molecular_function	iron ion binding
D	0006707	biological_process	cholesterol catabolic process
D	0008395	molecular_function	steroid hydroxylase activity
D	0009102	biological_process	biotin biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
D	0020037	molecular_function	heme binding
D	0036199	molecular_function	cholest-4-en-3-one 26-monooxygenase activity
D	0046872	molecular_function	metal ion binding
E	0000035	molecular_function	acyl binding
E	0000036	molecular_function	acyl carrier activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006629	biological_process	lipid metabolic process
E	0006631	biological_process	fatty acid metabolic process
E	0006633	biological_process	fatty acid biosynthetic process
E	0008289	molecular_function	lipid binding
E	0008610	biological_process	lipid biosynthetic process
E	0009245	biological_process	lipid A biosynthetic process
E	0009410	biological_process	response to xenobiotic stimulus
E	0031177	molecular_function	phosphopantetheine binding
F	0004497	molecular_function	monooxygenase activity
F	0005506	molecular_function	iron ion binding
F	0006707	biological_process	cholesterol catabolic process
F	0008395	molecular_function	steroid hydroxylase activity
F	0009102	biological_process	biotin biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
F	0020037	molecular_function	heme binding
F	0036199	molecular_function	cholest-4-en-3-one 26-monooxygenase activity
F	0046872	molecular_function	metal ion binding
G	0000035	molecular_function	acyl binding
G	0000036	molecular_function	acyl carrier activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006629	biological_process	lipid metabolic process
G	0006631	biological_process	fatty acid metabolic process
G	0006633	biological_process	fatty acid biosynthetic process
G	0008289	molecular_function	lipid binding
G	0008610	biological_process	lipid biosynthetic process
G	0009245	biological_process	lipid A biosynthetic process
G	0009410	biological_process	response to xenobiotic stimulus
G	0031177	molecular_function	phosphopantetheine binding
H	0004497	molecular_function	monooxygenase activity
H	0005506	molecular_function	iron ion binding
H	0006707	biological_process	cholesterol catabolic process
H	0008395	molecular_function	steroid hydroxylase activity
H	0009102	biological_process	biotin biosynthetic process
H	0016491	molecular_function	oxidoreductase activity
H	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
H	0020037	molecular_function	heme binding
H	0036199	molecular_function	cholest-4-en-3-one 26-monooxygenase activity
H	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00086
Number of Residues	10
Details	CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGhGHHVCLG

Chain	Residue	Details
B	PHE337-GLY346

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site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGADSLDTVELVMAL

Chain	Residue	Details
A	ASP51-LEU66

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING:

Chain	Residue	Details
B	ARG59
D	THR284
D	TYR306
D	HIS342
F	ARG59
F	HIS88
F	ILE168
F	THR284
F	TYR306
F	HIS342
H	ARG59
B	HIS88
H	HIS88
H	ILE168
H	THR284
H	TYR306
H	HIS342
B	ILE168
B	THR284
B	TYR306
B	HIS342
D	ARG59
D	HIS88
D	ILE168

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: axial binding residue

Chain	Residue	Details
B	CYS344
D	CYS344
F	CYS344
H	CYS344

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