3E9H
Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with L-Lysylsulfamoyl adenosine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004824 | molecular_function | lysine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0140096 | molecular_function | catalytic activity, acting on a protein |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004824 | molecular_function | lysine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016874 | molecular_function | ligase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0140096 | molecular_function | catalytic activity, acting on a protein |
| C | 0000049 | molecular_function | tRNA binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| C | 0004824 | molecular_function | lysine-tRNA ligase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006412 | biological_process | translation |
| C | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| C | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016874 | molecular_function | ligase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0140096 | molecular_function | catalytic activity, acting on a protein |
| D | 0000049 | molecular_function | tRNA binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| D | 0004824 | molecular_function | lysine-tRNA ligase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006412 | biological_process | translation |
| D | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| D | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016874 | molecular_function | ligase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0140096 | molecular_function | catalytic activity, acting on a protein |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 2001 |
| Chain | Residue |
| A | ARG402 |
| A | GLU404 |
| A | GLU411 |
| A | ASN414 |
| A | KAA2002 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE KAA A 2002 |
| Chain | Residue |
| A | ARG260 |
| A | HIS261 |
| A | ASN262 |
| A | PHE265 |
| A | MET267 |
| A | GLU269 |
| A | TYR271 |
| A | GLU411 |
| A | HIS412 |
| A | ALA413 |
| A | ASN414 |
| A | PHE416 |
| A | GLU418 |
| A | GLY463 |
| A | GLY467 |
| A | ARG470 |
| A | ILE481 |
| A | HOH509 |
| A | HOH730 |
| A | HOH846 |
| A | MG2001 |
| A | GLY207 |
| A | GLU231 |
| A | ARG253 |
| A | GLU255 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 2002 |
| Chain | Residue |
| B | ARG402 |
| B | GLU404 |
| B | GLU411 |
| B | ASN414 |
| B | KAA2003 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE KAA B 2003 |
| Chain | Residue |
| B | GLY207 |
| B | GLU231 |
| B | ARG253 |
| B | GLU255 |
| B | ARG260 |
| B | HIS261 |
| B | ASN262 |
| B | PHE265 |
| B | MET267 |
| B | GLU269 |
| B | TYR271 |
| B | GLU411 |
| B | HIS412 |
| B | ALA413 |
| B | ASN414 |
| B | PHE416 |
| B | GLU418 |
| B | GLY467 |
| B | ARG470 |
| B | ILE481 |
| B | HOH503 |
| B | HOH963 |
| B | MG2002 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 2003 |
| Chain | Residue |
| C | ARG402 |
| C | GLU404 |
| C | GLU411 |
| C | ASN414 |
| C | KAA2004 |
| site_id | AC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE KAA C 2004 |
| Chain | Residue |
| C | GLY207 |
| C | GLU231 |
| C | ARG253 |
| C | GLU255 |
| C | ARG260 |
| C | HIS261 |
| C | ASN262 |
| C | PHE265 |
| C | MET267 |
| C | GLU269 |
| C | TYR271 |
| C | GLU411 |
| C | HIS412 |
| C | ALA413 |
| C | ASN414 |
| C | PHE416 |
| C | GLU418 |
| C | GLY463 |
| C | GLY467 |
| C | ARG470 |
| C | ILE481 |
| C | HOH559 |
| C | HOH677 |
| C | HOH738 |
| C | MG2003 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 2004 |
| Chain | Residue |
| D | ARG402 |
| D | GLU404 |
| D | GLU411 |
| D | ASN414 |
| D | KAA2005 |
| site_id | AC8 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE KAA D 2005 |
| Chain | Residue |
| D | ASN262 |
| D | PHE265 |
| D | MET267 |
| D | GLU269 |
| D | TYR271 |
| D | GLU411 |
| D | HIS412 |
| D | ALA413 |
| D | ASN414 |
| D | PHE416 |
| D | GLU418 |
| D | GLY467 |
| D | ARG470 |
| D | ILE481 |
| D | HOH779 |
| D | HOH780 |
| D | MG2004 |
| D | GLY207 |
| D | GLU231 |
| D | ARG253 |
| D | GLU255 |
| D | ARG260 |
| D | HIS261 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| A | GLU269 | |
| A | ARG470 | |
| A | ARG253 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| B | GLU269 | |
| B | ARG470 | |
| B | ARG253 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| C | GLU269 | |
| C | ARG470 | |
| C | ARG253 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| D | GLU269 | |
| D | ARG470 | |
| D | ARG253 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| A | ARG253 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| B | ARG253 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| C | ARG253 |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| D | ARG253 |
