3E9E
Structure of full-length H11A mutant form of TIGAR from Danio rerio
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004331 | molecular_function | fructose-2,6-bisphosphate 2-phosphatase activity |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0005739 | cellular_component | mitochondrion |
A | 0005741 | cellular_component | mitochondrial outer membrane |
A | 0005829 | cellular_component | cytosol |
A | 0006914 | biological_process | autophagy |
A | 0006915 | biological_process | apoptotic process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0043456 | biological_process | regulation of pentose-phosphate shunt |
A | 0045820 | biological_process | negative regulation of glycolytic process |
B | 0003824 | molecular_function | catalytic activity |
B | 0004331 | molecular_function | fructose-2,6-bisphosphate 2-phosphatase activity |
B | 0005634 | cellular_component | nucleus |
B | 0005737 | cellular_component | cytoplasm |
B | 0005739 | cellular_component | mitochondrion |
B | 0005741 | cellular_component | mitochondrial outer membrane |
B | 0005829 | cellular_component | cytosol |
B | 0006914 | biological_process | autophagy |
B | 0006915 | biological_process | apoptotic process |
B | 0016787 | molecular_function | hydrolase activity |
B | 0043456 | biological_process | regulation of pentose-phosphate shunt |
B | 0045820 | biological_process | negative regulation of glycolytic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 A 266 |
Chain | Residue |
A | ARG10 |
A | ARG61 |
A | GLU89 |
A | HIS183 |
A | GLY184 |
A | HOH304 |
A | HOH359 |
A | HOH393 |
site_id | AC2 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE PO4 B 266 |
Chain | Residue |
B | ASN17 |
B | GLN23 |
B | ARG61 |
B | GLU89 |
B | HIS183 |
B | GLY184 |
B | ASN217 |
B | HOH353 |
B | ARG10 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Tele-phosphohistidine intermediate => ECO:0000269|PubMed:19015259 |
Chain | Residue | Details |
A | ALA11 | |
B | ALA11 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:19015259 |
Chain | Residue | Details |
A | GLU89 | |
B | GLU89 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | SITE: Transition state stabilizer => ECO:0000305|PubMed:19015259 |
Chain | Residue | Details |
A | HIS183 | |
B | HIS183 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 6 |
Details | Annotated By Reference To The Literature 2bif |
Chain | Residue | Details |
A | ARG61 | |
A | ASN17 | |
A | ARG10 | |
A | HIS183 | |
A | ALA11 | |
A | GLU89 |
site_id | CSA2 |
Number of Residues | 6 |
Details | Annotated By Reference To The Literature 2bif |
Chain | Residue | Details |
B | ARG61 | |
B | ASN17 | |
B | ARG10 | |
B | HIS183 | |
B | ALA11 | |
B | GLU89 |