3E95

Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004842	molecular_function	ubiquitin-protein transferase activity
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0006301	biological_process	DNA damage tolerance
A	0016740	molecular_function	transferase activity
A	0016874	molecular_function	ligase activity
A	0061631	molecular_function	ubiquitin conjugating enzyme activity
A	0070534	biological_process	protein K63-linked ubiquitination
B	0000166	molecular_function	nucleotide binding
B	0004842	molecular_function	ubiquitin-protein transferase activity
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0006301	biological_process	DNA damage tolerance
B	0016740	molecular_function	transferase activity
B	0016874	molecular_function	ligase activity
B	0061631	molecular_function	ubiquitin conjugating enzyme activity
B	0070534	biological_process	protein K63-linked ubiquitination
C	0004842	molecular_function	ubiquitin-protein transferase activity
C	0005634	cellular_component	nucleus
C	0006301	biological_process	DNA damage tolerance
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0016874	molecular_function	ligase activity
C	0031371	cellular_component	ubiquitin conjugating enzyme complex
C	0070534	biological_process	protein K63-linked ubiquitination

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE UNX B 250

Chain	Residue
B	UNX251
B	UNX252
B	UNX253
B	UNX254

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE UNX B 251

Chain	Residue
B	ASN132
B	UNX250
B	UNX252
B	UNX253
B	UNX254

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE UNX B 252

Chain	Residue
B	ASP130
B	UNX250
B	UNX251
B	UNX253
B	UNX254

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE UNX B 253

Chain	Residue
B	UNX250
B	UNX251
B	UNX252
B	UNX254

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE UNX B 254

Chain	Residue
B	ASP130
B	UNX250
B	UNX251
B	UNX252
B	UNX253

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Functional Information from PROSITE/UniProt

site_id	PS00183
Number of Residues	16
Details	UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNIdkl.GrICLdiL

Chain	Residue	Details
A	TYR74-LEU89

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