3E8J
Coproporphyrinogen III oxidase from Leishmania naiffi
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004109 | molecular_function | coproporphyrinogen oxidase activity |
| A | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| A | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| A | 0006783 | biological_process | heme biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0004109 | molecular_function | coproporphyrinogen oxidase activity |
| B | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| B | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| B | 0006783 | biological_process | heme biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 302 |
| Chain | Residue |
| A | VAL95 |
| A | HIS107 |
| A | ARG181 |
| A | TYR241 |
| A | ASN245 |
| A | SER268 |
| A | HOH317 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 303 |
| Chain | Residue |
| A | HOH367 |
| A | PHE173 |
| A | LYS298 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 304 |
| Chain | Residue |
| A | TRP167 |
| A | GLU170 |
| A | HOH403 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 305 |
| Chain | Residue |
| A | VAL123 |
| A | TRP124 |
| A | ASN192 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 302 |
| Chain | Residue |
| B | VAL95 |
| B | HIS107 |
| B | ARG181 |
| B | TYR241 |
| B | ASN245 |
| B | HOH421 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 303 |
| Chain | Residue |
| B | TRP167 |
| B | GLU170 |
| B | HOH413 |
| B | HOH438 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL B 304 |
| Chain | Residue |
| B | LYS298 |
Functional Information from PROSITE/UniProt
| site_id | PS01021 |
| Number of Residues | 25 |
| Details | COPROGEN_OXIDASE Coproporphyrinogen III oxidase signature. KaWCdeYFfIpHRnEaRGIGGLFFD |
| Chain | Residue | Details |
| A | LYS165-ASP189 |
