3E7X

Crystal structure of DLTA: implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0016874	molecular_function	ligase activity
A	0047473	molecular_function	D-alanine [D-alanyl carrier protein] ligase activity
A	0070395	biological_process	lipoteichoic acid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE AMP A 512

Chain	Residue
A	GLY269
A	ARG396
A	LYS402
A	ARG407
A	HOH515
A	HOH529
A	HOH658
A	HOH718
A	GLU270
A	ASN291
A	THR292
A	TYR293
A	GLY294
A	PRO295
A	THR296
A	ASP382

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Functional Information from PROSITE/UniProt

site_id	PS00455
Number of Residues	12
Details	AMP_BINDING Putative AMP-binding domain signature. IIYTSGSTGnPK

Chain	Residue	Details
A	ILE148-LYS159

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00593

Chain	Residue	Details
A	ASP196
A	VAL300
A	LYS491
A	THR151

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00593, ECO:0000269|PubMed:18784082, ECO:0007744|PDB:3E7W, ECO:0007744|PDB:3E7X

Chain	Residue	Details
A	ASP382
A	ASN291

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:18784082, ECO:0007744|PDB:3E7W, ECO:0007744|PDB:3E7X

Chain	Residue	Details
A	ARG407

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