3E6U

Crystal structure of Human LanCL1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0004930	molecular_function	G protein-coupled receptor activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0005975	biological_process	carbohydrate metabolic process
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0008270	molecular_function	zinc ion binding
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0017124	molecular_function	SH3 domain binding
A	0031179	biological_process	peptide modification
A	0043295	molecular_function	glutathione binding
A	0046872	molecular_function	metal ion binding
A	0050750	molecular_function	low-density lipoprotein particle receptor binding
A	1990748	biological_process	cellular detoxification
B	0004364	molecular_function	glutathione transferase activity
B	0004930	molecular_function	G protein-coupled receptor activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0005975	biological_process	carbohydrate metabolic process
B	0007186	biological_process	G protein-coupled receptor signaling pathway
B	0008270	molecular_function	zinc ion binding
B	0016020	cellular_component	membrane
B	0016740	molecular_function	transferase activity
B	0017124	molecular_function	SH3 domain binding
B	0031179	biological_process	peptide modification
B	0043295	molecular_function	glutathione binding
B	0046872	molecular_function	metal ion binding
B	0050750	molecular_function	low-density lipoprotein particle receptor binding
B	1990748	biological_process	cellular detoxification
C	0004364	molecular_function	glutathione transferase activity
C	0004930	molecular_function	G protein-coupled receptor activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005886	cellular_component	plasma membrane
C	0005975	biological_process	carbohydrate metabolic process
C	0007186	biological_process	G protein-coupled receptor signaling pathway
C	0008270	molecular_function	zinc ion binding
C	0016020	cellular_component	membrane
C	0016740	molecular_function	transferase activity
C	0017124	molecular_function	SH3 domain binding
C	0031179	biological_process	peptide modification
C	0043295	molecular_function	glutathione binding
C	0046872	molecular_function	metal ion binding
C	0050750	molecular_function	low-density lipoprotein particle receptor binding
C	1990748	biological_process	cellular detoxification
D	0004364	molecular_function	glutathione transferase activity
D	0004930	molecular_function	G protein-coupled receptor activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005886	cellular_component	plasma membrane
D	0005975	biological_process	carbohydrate metabolic process
D	0007186	biological_process	G protein-coupled receptor signaling pathway
D	0008270	molecular_function	zinc ion binding
D	0016020	cellular_component	membrane
D	0016740	molecular_function	transferase activity
D	0017124	molecular_function	SH3 domain binding
D	0031179	biological_process	peptide modification
D	0043295	molecular_function	glutathione binding
D	0046872	molecular_function	metal ion binding
D	0050750	molecular_function	low-density lipoprotein particle receptor binding
D	1990748	biological_process	cellular detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 501

Chain	Residue
A	CYS276
A	CYS322
A	HIS323
C	HIS-7

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 502

Chain	Residue
A	HIS-7
C	CYS276
C	CYS322
C	HIS323

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 503

Chain	Residue
B	CYS276
B	CYS322
B	HIS323
B	HOH572
B	TYR62

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 504

Chain	Residue
D	TYR62
D	CYS276
D	CYS322
D	HIS323
D	HOH548

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19528316","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---