Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3E6Q

Putative 5-carboxymethyl-2-hydroxymuconate isomerase from Pseudomonas aeruginosa.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
A	0009056	biological_process	catabolic process
B	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
B	0009056	biological_process	catabolic process
C	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
C	0009056	biological_process	catabolic process
D	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
D	0009056	biological_process	catabolic process
E	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
E	0009056	biological_process	catabolic process
F	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
F	0009056	biological_process	catabolic process
G	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
G	0009056	biological_process	catabolic process
H	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
H	0009056	biological_process	catabolic process
I	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
I	0009056	biological_process	catabolic process
J	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
J	0009056	biological_process	catabolic process
K	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
K	0009056	biological_process	catabolic process
L	0008704	molecular_function	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
L	0009056	biological_process	catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 310

Chain	Residue
A	GLN101
A	HOH389
B	VAL118
B	HOH489

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT A 325

Chain	Residue
A	ARG51
A	HOH365
B	GLU23
F	GLU48

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT A 333

Chain	Residue
A	HOH355
A	HOH375
A	HOH431
A	ARG111

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT A 335

Chain	Residue
A	HIS63
A	CYS65
A	GLU105
B	FMT345
B	HOH477

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 337

Chain	Residue
A	ALA8
A	THR9
A	ALA10
A	LEU12
A	THR46
A	HOH418

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 343

Chain	Residue
A	VAL5
A	GLU7
A	HIS63
A	CYS65
B	HOH383

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 304

Chain	Residue
A	ARG107
B	ARG107
B	HOH373
C	ARG107

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO B 309

Chain	Residue
A	GLU48
B	PHE44
B	VAL45
B	THR46
B	HOH361
B	HOH374
B	HOH381

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT B 332

Chain	Residue
B	ARG111
B	HOH430
B	HOH452
K	HOH464

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA B 344

Chain	Residue
B	GLU7
B	HOH494

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FMT B 345

Chain	Residue
A	FMT335
B	HIS3
B	VAL5
B	SER67
B	HOH346
B	HOH402
B	HOH477

site_id	BC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GOL C 303

Chain	Residue
A	ARG107
A	GLU108
A	HOH405
B	ARG107
B	GLU108
B	HOH470
C	ARG107
C	GLU108
C	HOH327
C	HOH336
C	HOH342
C	HOH429
C	HOH457

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO C 318

Chain	Residue
A	HIS3
A	SER67
A	HOH345
C	HIS63
C	CYS65
C	GLU105
C	HOH358

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO D 313

Chain	Residue
D	HIS63
D	CYS65
D	GLU105
D	HOH344
E	HIS3
E	ARG107
E	HOH418

site_id	BC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL E 301

Chain	Residue
D	ARG107
D	GLU108
E	ARG107
E	GLU108
E	HOH421
E	HOH422
E	HOH437
E	HOH497
E	HOH541
F	ARG107
F	GLU108

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL E 306

Chain	Residue
A	GLU48
A	HOH415
E	GLU48
E	ALA49
E	TYR50
E	ARG51
E	HOH427
E	HOH534

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO E 322

Chain	Residue
E	CYS65
E	GLU105
E	HOH475
F	HIS3
F	ARG43
F	SER67
F	ARG107
E	HIS63

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT E 338

Chain	Residue
D	ARG107
E	ARG107
F	ARG107

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO F 312

Chain	Residue
D	HIS3
D	HOH322
F	HIS63
F	CYS65
F	GLU105
F	HOH498

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT F 324

Chain	Residue
F	THR9
F	LEU12
F	HOH439

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT F 326

Chain	Residue
F	ASP39
G	GLN34
G	HOH494

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA F 342

Chain	Residue
E	HOH464
F	VAL5
F	GLU7
F	HIS63
F	CYS65

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO G 319

Chain	Residue
G	HIS63
G	CYS65
G	GLU105
G	HOH582
H	HIS3
H	HOH341

site_id	CC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA G 341

Chain	Residue
G	GLU7

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL H 302

Chain	Residue
G	ARG107
H	ARG107
H	HOH406
H	HOH411
I	ARG107

site_id	CC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL H 305

Chain	Residue
G	ARG107
H	ARG107
H	GLU108
H	HOH357
H	HOH367
H	HOH368
H	HOH473
I	ARG107
I	GLU108

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO H 311

Chain	Residue
H	HIS63
H	CYS65
H	GLU105
H	HOH382

site_id	DC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO H 321

Chain	Residue
H	TYR50
H	ARG51
H	HOH342
H	HOH471
I	GLY19
I	LEU22
I	HOH365

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT H 327

Chain	Residue
H	ARG13
H	ALA93
H	HOH460
K	SER17

site_id	DC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FMT H 328

Chain	Residue
H	HOH470

site_id	DC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT H 334

Chain	Residue
H	ALA8
H	THR9
H	LEU12
H	THR46
H	HOH385

site_id	DC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO I 314

Chain	Residue
H	GLU48
I	PHE44
I	VAL45
I	THR46
I	HOH342
I	HOH391
I	HOH403

site_id	DC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO I 315

Chain	Residue
H	ARG51
I	GLU20
I	GLU23
I	HOH340
I	HOH365
I	HOH383
L	GLU48

site_id	DC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO I 317

Chain	Residue
G	HIS3
G	ARG43
I	HIS63
I	CYS65
I	GLU105
I	HOH478

site_id	DC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT I 329

Chain	Residue
I	GLU7
I	HOH434

site_id	DC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FMT I 330

Chain	Residue
I	GLU48
I	ALA49
I	TYR50
I	ARG51
I	HOH400
I	HOH508

site_id	EC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL J 307

Chain	Residue
J	ARG107
J	GLU108
J	HOH356
J	HOH360
J	HOH374
J	HOH416
J	HOH458
J	HOH478
K	ARG107
L	ARG107
L	GLU108

site_id	EC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO J 316

Chain	Residue
J	HIS63
J	CYS65
J	GLU105
J	HOH382
K	ARG43
K	SER67

site_id	EC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IMD J 340

Chain	Residue
J	ARG107
K	ARG107
L	ARG107

site_id	EC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO K 308

Chain	Residue
H	GLU48
K	GLU48
K	ALA49
K	TYR50
K	ARG51

site_id	EC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EDO K 323

Chain	Residue
K	GLU7
K	HIS63
K	CYS65
K	GLU105
K	EDO324
K	HOH454
K	HOH485
L	VAL5
L	HOH394

site_id	EC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO K 324

Chain	Residue
K	HIS63
K	CYS65
K	GLU105
K	EDO323
L	HIS3
L	SER67
L	ARG107
L	MSE109

site_id	EC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO L 320

Chain	Residue
A	GLN34
A	HOH373
L	PHE-2
L	GLY36
L	ASP39

site_id	EC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FMT L 331

Chain	Residue
L	LEU-4

site_id	EC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT L 336

Chain	Residue
L	ASP73
L	FMT340
L	HOH502
L	HOH510

site_id	FC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE IMD L 339

Chain	Residue
I	SER17
L	ALA8
L	THR9
L	ALA10
L	LEU12
L	LEU14
L	PHE44
L	THR46
L	HOH448

site_id	FC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT L 340

Chain	Residue
L	ARG72
L	ASP73
L	THR76
L	FMT336

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
A	PRO2
A	PHE35
A	LYS41

site_id	CSA10
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
J	PRO2
J	PHE35
J	LYS41

site_id	CSA11
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
K	PRO2
K	PHE35
K	LYS41

site_id	CSA12
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
L	PRO2
L	PHE35
L	LYS41

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
B	PRO2
B	PHE35
B	LYS41

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
C	PRO2
C	PHE35
C	LYS41

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
D	PRO2
D	PHE35
D	LYS41

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
E	PRO2
E	PHE35
E	LYS41

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
F	PRO2
F	PHE35
F	LYS41

site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
G	PRO2
G	PHE35
G	LYS41

site_id	CSA8
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
H	PRO2
H	PHE35
H	LYS41

site_id	CSA9
Number of Residues	3
Details	Annotated By Reference To The Literature 1otg

Chain	Residue	Details
I	PRO2
I	PHE35
I	LYS41

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)