3E6Q
Putative 5-carboxymethyl-2-hydroxymuconate isomerase from Pseudomonas aeruginosa.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| A | 0009056 | biological_process | catabolic process |
| B | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| B | 0009056 | biological_process | catabolic process |
| C | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| C | 0009056 | biological_process | catabolic process |
| D | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| D | 0009056 | biological_process | catabolic process |
| E | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| E | 0009056 | biological_process | catabolic process |
| F | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| F | 0009056 | biological_process | catabolic process |
| G | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| G | 0009056 | biological_process | catabolic process |
| H | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| H | 0009056 | biological_process | catabolic process |
| I | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| I | 0009056 | biological_process | catabolic process |
| J | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| J | 0009056 | biological_process | catabolic process |
| K | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| K | 0009056 | biological_process | catabolic process |
| L | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| L | 0009056 | biological_process | catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 310 |
| Chain | Residue |
| A | GLN101 |
| A | HOH389 |
| B | VAL118 |
| B | HOH489 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 325 |
| Chain | Residue |
| A | ARG51 |
| A | HOH365 |
| B | GLU23 |
| F | GLU48 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 333 |
| Chain | Residue |
| A | HOH355 |
| A | HOH375 |
| A | HOH431 |
| A | ARG111 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 335 |
| Chain | Residue |
| A | HIS63 |
| A | CYS65 |
| A | GLU105 |
| B | FMT345 |
| B | HOH477 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 337 |
| Chain | Residue |
| A | ALA8 |
| A | THR9 |
| A | ALA10 |
| A | LEU12 |
| A | THR46 |
| A | HOH418 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 343 |
| Chain | Residue |
| A | VAL5 |
| A | GLU7 |
| A | HIS63 |
| A | CYS65 |
| B | HOH383 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 304 |
| Chain | Residue |
| A | ARG107 |
| B | ARG107 |
| B | HOH373 |
| C | ARG107 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 309 |
| Chain | Residue |
| A | GLU48 |
| B | PHE44 |
| B | VAL45 |
| B | THR46 |
| B | HOH361 |
| B | HOH374 |
| B | HOH381 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT B 332 |
| Chain | Residue |
| B | ARG111 |
| B | HOH430 |
| B | HOH452 |
| K | HOH464 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA B 344 |
| Chain | Residue |
| B | GLU7 |
| B | HOH494 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT B 345 |
| Chain | Residue |
| A | FMT335 |
| B | HIS3 |
| B | VAL5 |
| B | SER67 |
| B | HOH346 |
| B | HOH402 |
| B | HOH477 |
| site_id | BC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GOL C 303 |
| Chain | Residue |
| A | ARG107 |
| A | GLU108 |
| A | HOH405 |
| B | ARG107 |
| B | GLU108 |
| B | HOH470 |
| C | ARG107 |
| C | GLU108 |
| C | HOH327 |
| C | HOH336 |
| C | HOH342 |
| C | HOH429 |
| C | HOH457 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 318 |
| Chain | Residue |
| A | HIS3 |
| A | SER67 |
| A | HOH345 |
| C | HIS63 |
| C | CYS65 |
| C | GLU105 |
| C | HOH358 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 313 |
| Chain | Residue |
| D | HIS63 |
| D | CYS65 |
| D | GLU105 |
| D | HOH344 |
| E | HIS3 |
| E | ARG107 |
| E | HOH418 |
| site_id | BC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL E 301 |
| Chain | Residue |
| D | ARG107 |
| D | GLU108 |
| E | ARG107 |
| E | GLU108 |
| E | HOH421 |
| E | HOH422 |
| E | HOH437 |
| E | HOH497 |
| E | HOH541 |
| F | ARG107 |
| F | GLU108 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL E 306 |
| Chain | Residue |
| A | GLU48 |
| A | HOH415 |
| E | GLU48 |
| E | ALA49 |
| E | TYR50 |
| E | ARG51 |
| E | HOH427 |
| E | HOH534 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO E 322 |
| Chain | Residue |
| E | CYS65 |
| E | GLU105 |
| E | HOH475 |
| F | HIS3 |
| F | ARG43 |
| F | SER67 |
| F | ARG107 |
| E | HIS63 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT E 338 |
| Chain | Residue |
| D | ARG107 |
| E | ARG107 |
| F | ARG107 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO F 312 |
| Chain | Residue |
| D | HIS3 |
| D | HOH322 |
| F | HIS63 |
| F | CYS65 |
| F | GLU105 |
| F | HOH498 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT F 324 |
| Chain | Residue |
| F | THR9 |
| F | LEU12 |
| F | HOH439 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT F 326 |
| Chain | Residue |
| F | ASP39 |
| G | GLN34 |
| G | HOH494 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA F 342 |
| Chain | Residue |
| E | HOH464 |
| F | VAL5 |
| F | GLU7 |
| F | HIS63 |
| F | CYS65 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO G 319 |
| Chain | Residue |
| G | HIS63 |
| G | CYS65 |
| G | GLU105 |
| G | HOH582 |
| H | HIS3 |
| H | HOH341 |
| site_id | CC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA G 341 |
| Chain | Residue |
| G | GLU7 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL H 302 |
| Chain | Residue |
| G | ARG107 |
| H | ARG107 |
| H | HOH406 |
| H | HOH411 |
| I | ARG107 |
| site_id | CC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL H 305 |
| Chain | Residue |
| G | ARG107 |
| H | ARG107 |
| H | GLU108 |
| H | HOH357 |
| H | HOH367 |
| H | HOH368 |
| H | HOH473 |
| I | ARG107 |
| I | GLU108 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO H 311 |
| Chain | Residue |
| H | HIS63 |
| H | CYS65 |
| H | GLU105 |
| H | HOH382 |
| site_id | DC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO H 321 |
| Chain | Residue |
| H | TYR50 |
| H | ARG51 |
| H | HOH342 |
| H | HOH471 |
| I | GLY19 |
| I | LEU22 |
| I | HOH365 |
| site_id | DC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT H 327 |
| Chain | Residue |
| H | ARG13 |
| H | ALA93 |
| H | HOH460 |
| K | SER17 |
| site_id | DC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT H 328 |
| Chain | Residue |
| H | HOH470 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT H 334 |
| Chain | Residue |
| H | ALA8 |
| H | THR9 |
| H | LEU12 |
| H | THR46 |
| H | HOH385 |
| site_id | DC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO I 314 |
| Chain | Residue |
| H | GLU48 |
| I | PHE44 |
| I | VAL45 |
| I | THR46 |
| I | HOH342 |
| I | HOH391 |
| I | HOH403 |
| site_id | DC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO I 315 |
| Chain | Residue |
| H | ARG51 |
| I | GLU20 |
| I | GLU23 |
| I | HOH340 |
| I | HOH365 |
| I | HOH383 |
| L | GLU48 |
| site_id | DC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO I 317 |
| Chain | Residue |
| G | HIS3 |
| G | ARG43 |
| I | HIS63 |
| I | CYS65 |
| I | GLU105 |
| I | HOH478 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT I 329 |
| Chain | Residue |
| I | GLU7 |
| I | HOH434 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT I 330 |
| Chain | Residue |
| I | GLU48 |
| I | ALA49 |
| I | TYR50 |
| I | ARG51 |
| I | HOH400 |
| I | HOH508 |
| site_id | EC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL J 307 |
| Chain | Residue |
| J | ARG107 |
| J | GLU108 |
| J | HOH356 |
| J | HOH360 |
| J | HOH374 |
| J | HOH416 |
| J | HOH458 |
| J | HOH478 |
| K | ARG107 |
| L | ARG107 |
| L | GLU108 |
| site_id | EC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO J 316 |
| Chain | Residue |
| J | HIS63 |
| J | CYS65 |
| J | GLU105 |
| J | HOH382 |
| K | ARG43 |
| K | SER67 |
| site_id | EC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IMD J 340 |
| Chain | Residue |
| J | ARG107 |
| K | ARG107 |
| L | ARG107 |
| site_id | EC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO K 308 |
| Chain | Residue |
| H | GLU48 |
| K | GLU48 |
| K | ALA49 |
| K | TYR50 |
| K | ARG51 |
| site_id | EC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO K 323 |
| Chain | Residue |
| K | GLU7 |
| K | HIS63 |
| K | CYS65 |
| K | GLU105 |
| K | EDO324 |
| K | HOH454 |
| K | HOH485 |
| L | VAL5 |
| L | HOH394 |
| site_id | EC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO K 324 |
| Chain | Residue |
| K | HIS63 |
| K | CYS65 |
| K | GLU105 |
| K | EDO323 |
| L | HIS3 |
| L | SER67 |
| L | ARG107 |
| L | MSE109 |
| site_id | EC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO L 320 |
| Chain | Residue |
| A | GLN34 |
| A | HOH373 |
| L | PHE-2 |
| L | GLY36 |
| L | ASP39 |
| site_id | EC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT L 331 |
| Chain | Residue |
| L | LEU-4 |
| site_id | EC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT L 336 |
| Chain | Residue |
| L | ASP73 |
| L | FMT340 |
| L | HOH502 |
| L | HOH510 |
| site_id | FC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE IMD L 339 |
| Chain | Residue |
| I | SER17 |
| L | ALA8 |
| L | THR9 |
| L | ALA10 |
| L | LEU12 |
| L | LEU14 |
| L | PHE44 |
| L | THR46 |
| L | HOH448 |
| site_id | FC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT L 340 |
| Chain | Residue |
| L | ARG72 |
| L | ASP73 |
| L | THR76 |
| L | FMT336 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| A | PRO2 | |
| A | PHE35 | |
| A | LYS41 |
| site_id | CSA10 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| J | PRO2 | |
| J | PHE35 | |
| J | LYS41 |
| site_id | CSA11 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| K | PRO2 | |
| K | PHE35 | |
| K | LYS41 |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| L | PRO2 | |
| L | PHE35 | |
| L | LYS41 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| B | PRO2 | |
| B | PHE35 | |
| B | LYS41 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| C | PRO2 | |
| C | PHE35 | |
| C | LYS41 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| D | PRO2 | |
| D | PHE35 | |
| D | LYS41 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| E | PRO2 | |
| E | PHE35 | |
| E | LYS41 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| F | PRO2 | |
| F | PHE35 | |
| F | LYS41 |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| G | PRO2 | |
| G | PHE35 | |
| G | LYS41 |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| H | PRO2 | |
| H | PHE35 | |
| H | LYS41 |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1otg |
| Chain | Residue | Details |
| I | PRO2 | |
| I | PHE35 | |
| I | LYS41 |
