3E6E
Crystal structure of Alanine racemase from E.faecalis complex with cycloserine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0008784 | molecular_function | alanine racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030632 | biological_process | D-alanine biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006522 | biological_process | alanine metabolic process |
| B | 0008784 | molecular_function | alanine racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0030632 | biological_process | D-alanine biosynthetic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006522 | biological_process | alanine metabolic process |
| C | 0008784 | molecular_function | alanine racemase activity |
| C | 0009252 | biological_process | peptidoglycan biosynthetic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0030632 | biological_process | D-alanine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE DCS A 372 |
| Chain | Residue |
| A | VAL38 |
| A | VAL225 |
| A | TYR356 |
| A | HOH374 |
| C | TYR267 |
| C | TYR286 |
| C | CYS313 |
| C | MET314 |
| A | LYS40 |
| A | TYR44 |
| A | LEU86 |
| A | ARG139 |
| A | HIS169 |
| A | SER207 |
| A | ARG222 |
| A | GLY224 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE DCS B 372 |
| Chain | Residue |
| B | VAL38 |
| B | LYS40 |
| B | TYR44 |
| B | ARG139 |
| B | HIS169 |
| B | SER207 |
| B | ARG222 |
| B | GLY224 |
| B | VAL225 |
| B | TYR267 |
| B | TYR286 |
| B | MET314 |
| B | TYR356 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE DCS C 372 |
| Chain | Residue |
| A | TYR267 |
| A | TYR286 |
| A | CYS313 |
| A | MET314 |
| C | LYS40 |
| C | TYR44 |
| C | LEU86 |
| C | ARG139 |
| C | HIS169 |
| C | ASN206 |
| C | SER207 |
| C | ARG222 |
| C | GLY224 |
| C | VAL225 |
| C | TYR356 |
| C | HOH374 |
Functional Information from PROSITE/UniProt
| site_id | PS00395 |
| Number of Residues | 11 |
| Details | ALANINE_RACEMASE Alanine racemase pyridoxal-phosphate attachment site. AVvKANGYGHG |
| Chain | Residue | Details |
| A | ALA37-GLY47 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bd0 |
| Chain | Residue | Details |
| A | LYS40 | |
| A | ARG139 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bd0 |
| Chain | Residue | Details |
| B | LYS40 | |
| B | ARG139 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bd0 |
| Chain | Residue | Details |
| C | LYS40 | |
| C | ARG139 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bd0 |
| Chain | Residue | Details |
| A | CYS313 | |
| A | TYR267 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bd0 |
| Chain | Residue | Details |
| B | CYS313 | |
| B | TYR267 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bd0 |
| Chain | Residue | Details |
| C | CYS313 | |
| C | TYR267 |
