Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0004518 | molecular_function | nuclease activity |
B | 0003676 | molecular_function | nucleic acid binding |
B | 0004518 | molecular_function | nuclease activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE THP A 150 |
Chain | Residue |
A | ARG35 |
A | HOH157 |
A | HOH159 |
A | HOH160 |
A | HOH183 |
A | HOH189 |
A | HOH208 |
A | LYS84 |
A | TYR85 |
A | ARG87 |
A | TYR113 |
A | TYR115 |
A | LYS127 |
A | CA151 |
A | HOH153 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE CA A 151 |
Chain | Residue |
A | ASP21 |
A | ARG35 |
A | ASP40 |
A | GLU43 |
A | THP150 |
A | HOH156 |
A | HOH208 |
A | HOH224 |
site_id | AC3 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE THP B 150 |
Chain | Residue |
B | ARG35 |
B | LYS84 |
B | TYR85 |
B | ARG87 |
B | LEU89 |
B | TYR113 |
B | TYR115 |
B | LYS127 |
B | CA151 |
B | HOH153 |
B | HOH159 |
B | HOH166 |
B | HOH172 |
B | HOH183 |
B | HOH196 |
B | HOH205 |
B | HOH226 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CA B 151 |
Chain | Residue |
B | ASP21 |
B | ASP40 |
B | THP150 |
B | HOH155 |
B | HOH167 |
Functional Information from PROSITE/UniProt
site_id | PS01123 |
Number of Residues | 25 |
Details | TNASE_1 Thermonuclease family signature 1. DGDTVkLmykgqpmtf.RLllVDtPE |
Chain | Residue | Details |
A | ASP19-GLU43 | |
site_id | PS01284 |
Number of Residues | 11 |
Details | TNASE_2 Thermonuclease family signature 2. DKYGRgLAyIY |
Chain | Residue | Details |
A | ASP83-TYR93 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ARG35 | |
A | GLU43 | |
A | TYR93 | |
B | ARG35 | |
B | GLU43 | |
B | TYR93 | |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | BINDING: |
Chain | Residue | Details |
A | ASP21 | |
A | ASP40 | |
A | THR41 | |
B | ASP21 | |
B | ASP40 | |
B | THR41 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a2t |
Chain | Residue | Details |
A | ARG35 | |
A | ARG87 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a2t |
Chain | Residue | Details |
B | ARG35 | |
B | ARG87 | |
site_id | MCSA1 |
Number of Residues | 6 |
Details | M-CSA 165 |
Chain | Residue | Details |
A | ASP21 | metal ligand |
A | ARG35 | electrostatic stabiliser, hydrogen bond donor |
A | ASP40 | metal ligand |
A | THR41 | metal ligand |
A | GLU43 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | TYR93 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
site_id | MCSA2 |
Number of Residues | 6 |
Details | M-CSA 165 |
Chain | Residue | Details |
B | ASP21 | metal ligand |
B | ARG35 | electrostatic stabiliser, hydrogen bond donor |
B | ASP40 | metal ligand |
B | THR41 | metal ligand |
B | GLU43 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
B | TYR93 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |