3E5P
Crystal structure of alanine racemase from E.faecalis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0008784 | molecular_function | alanine racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030632 | biological_process | D-alanine biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006522 | biological_process | alanine metabolic process |
| B | 0008784 | molecular_function | alanine racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0030632 | biological_process | D-alanine biosynthetic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006522 | biological_process | alanine metabolic process |
| C | 0008784 | molecular_function | alanine racemase activity |
| C | 0009252 | biological_process | peptidoglycan biosynthetic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0030632 | biological_process | D-alanine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PLP A 390 |
| Chain | Residue |
| A | LYS40 |
| A | HOH431 |
| A | TYR44 |
| A | HIS169 |
| A | ASN206 |
| A | SER207 |
| A | ARG222 |
| A | GLY224 |
| A | VAL225 |
| A | TYR356 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PPI A 400 |
| Chain | Residue |
| A | TYR267 |
| A | TYR286 |
| A | CYS313 |
| A | MET314 |
| C | TYR356 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EPE A 430 |
| Chain | Residue |
| A | ARG292 |
| A | HIS293 |
| A | GLN295 |
| A | ARG311 |
| A | LYS350 |
| C | GLU352 |
| C | THR353 |
| C | 2PE401 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PLP B 390 |
| Chain | Residue |
| B | LYS40 |
| B | TYR44 |
| B | ARG139 |
| B | HIS169 |
| B | ASN206 |
| B | SER207 |
| B | ARG222 |
| B | GLY224 |
| B | VAL225 |
| B | TYR356 |
| B | HOH402 |
| B | HOH403 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PPI B 400 |
| Chain | Residue |
| B | TYR267 |
| B | TYR286 |
| B | ILE354 |
| B | TYR356 |
| B | HOH422 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 2PE C 401 |
| Chain | Residue |
| A | HIS293 |
| A | LYS350 |
| A | LEU351 |
| A | GLU352 |
| A | ILE354 |
| A | EPE430 |
| C | ARG292 |
| C | HIS293 |
| C | GLN295 |
| C | ARG311 |
| C | LYS350 |
| C | GLU352 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PLP C 390 |
| Chain | Residue |
| C | VAL38 |
| C | LYS40 |
| C | TYR44 |
| C | LEU86 |
| C | HIS169 |
| C | ASN206 |
| C | SER207 |
| C | ARG222 |
| C | GLY224 |
| C | VAL225 |
| C | TYR356 |
| C | HOH425 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PPI C 400 |
| Chain | Residue |
| C | TYR267 |
| C | TYR286 |
| C | CYS313 |
| C | MET314 |
Functional Information from PROSITE/UniProt
| site_id | PS00395 |
| Number of Residues | 11 |
| Details | ALANINE_RACEMASE Alanine racemase pyridoxal-phosphate attachment site. AVvKANGYGHG |
| Chain | Residue | Details |
| A | ALA37-GLY47 |
