3E4Y

Crystal structure of a 33kDa catalase-related protein from Mycobacterium avium subsp. paratuberculosis. I2(1)2(1)2(1) crystal form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004096	molecular_function	catalase activity
A	0004601	molecular_function	peroxidase activity
A	0005506	molecular_function	iron ion binding
A	0005737	cellular_component	cytoplasm
A	0005777	cellular_component	peroxisome
A	0006979	biological_process	response to oxidative stress
A	0020037	molecular_function	heme binding
A	0042542	biological_process	response to hydrogen peroxide
A	0042743	biological_process	hydrogen peroxide metabolic process
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0046872	molecular_function	metal ion binding
A	0098869	biological_process	cellular oxidant detoxification
A	2000377	biological_process	regulation of reactive oxygen species metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM A 501

Chain	Residue
A	ARG25
A	PHE113
A	HIS163
A	GLY164
A	PHE270
A	ARG290
A	TYR294
A	SER297
A	ARG301
A	GOL610
A	HOH721
A	ALA26
A	HOH773
A	LEU27
A	HIS28
A	ARG63
A	SER98
A	ALA99
A	GLN100
A	LEU105

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 610

Chain	Residue
A	HIS28
A	GLN100
A	LEU105
A	HEM501

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 620

Chain	Residue
A	ARG103
A	HIS183
A	THR187
A	ALA189
A	ARG224

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 A 710

Chain	Residue
A	HIS263
A	GLY264
A	HOH828

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P04040

Chain	Residue	Details
A	HIS28

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: axial binding residue

Chain	Residue	Details
A	TYR294

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