3E4D
Structural and Kinetic Study of an S-Formylglutathione Hydrolase from Agrobacterium tumefaciens
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0018738 | molecular_function | S-formylglutathione hydrolase activity |
| A | 0046292 | biological_process | formaldehyde metabolic process |
| A | 0046294 | biological_process | formaldehyde catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0018738 | molecular_function | S-formylglutathione hydrolase activity |
| B | 0046292 | biological_process | formaldehyde metabolic process |
| B | 0046294 | biological_process | formaldehyde catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0018738 | molecular_function | S-formylglutathione hydrolase activity |
| C | 0046292 | biological_process | formaldehyde metabolic process |
| C | 0046294 | biological_process | formaldehyde catabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0018738 | molecular_function | S-formylglutathione hydrolase activity |
| D | 0046292 | biological_process | formaldehyde metabolic process |
| D | 0046294 | biological_process | formaldehyde catabolic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| E | 0005829 | cellular_component | cytosol |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0018738 | molecular_function | S-formylglutathione hydrolase activity |
| E | 0046292 | biological_process | formaldehyde metabolic process |
| E | 0046294 | biological_process | formaldehyde catabolic process |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| F | 0005829 | cellular_component | cytosol |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0018738 | molecular_function | S-formylglutathione hydrolase activity |
| F | 0046292 | biological_process | formaldehyde metabolic process |
| F | 0046294 | biological_process | formaldehyde catabolic process |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0052689 | molecular_function | carboxylic ester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 278 |
| Chain | Residue |
| A | ASP90 |
| A | GLU91 |
| A | ASN94 |
| A | HOH368 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 279 |
| Chain | Residue |
| A | LEU52 |
| A | SER147 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 280 |
| Chain | Residue |
| A | SER224 |
| A | ASP255 |
| A | HIS256 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 278 |
| Chain | Residue |
| B | ASP90 |
| B | GLU91 |
| B | ASN94 |
| B | HOH292 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 279 |
| Chain | Residue |
| B | LEU52 |
| B | SER147 |
| B | HOH304 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 280 |
| Chain | Residue |
| B | SER224 |
| B | ASP255 |
| B | HIS256 |
| B | HOH281 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 278 |
| Chain | Residue |
| C | ASP90 |
| C | GLU91 |
| C | ASN94 |
| C | HOH405 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG E 278 |
| Chain | Residue |
| E | ASP90 |
| E | GLU91 |
| E | ASN94 |
| E | HOH358 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL E 279 |
| Chain | Residue |
| E | LEU52 |
| E | SER147 |
| E | HOH316 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL E 280 |
| Chain | Residue |
| E | SER224 |
| E | HIS256 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG D 278 |
| Chain | Residue |
| D | ASP90 |
| D | GLU91 |
| D | ASN94 |
| D | HOH352 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 279 |
| Chain | Residue |
| D | LEU52 |
| D | SER147 |
| D | HOH354 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG F 278 |
| Chain | Residue |
| F | ASP90 |
| F | GLU91 |
| F | ASN94 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL F 279 |
| Chain | Residue |
| F | LEU52 |
| F | SER147 |
| F | HOH330 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL F 280 |
| Chain | Residue |
| F | SER224 |
| F | ASP255 |
| F | HIS256 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 279 |
| Chain | Residue |
| C | LEU52 |
| C | SER147 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 280 |
| Chain | Residue |
| C | SER224 |
| C | ASP255 |
| C | HIS256 |
| C | HOH282 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 280 |
| Chain | Residue |
| D | SER224 |
| D | ASP255 |
| D | HIS256 |
| D | HOH355 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qfm |
| Chain | Residue | Details |
| A | ASP223 | |
| A | HIS256 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qfm |
| Chain | Residue | Details |
| B | ASP223 | |
| B | HIS256 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qfm |
| Chain | Residue | Details |
| C | ASP223 | |
| C | HIS256 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qfm |
| Chain | Residue | Details |
| E | ASP223 | |
| E | HIS256 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qfm |
| Chain | Residue | Details |
| D | ASP223 | |
| D | HIS256 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qfm |
| Chain | Residue | Details |
| F | ASP223 | |
| F | HIS256 |
