Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 1 |
| Chain | Residue |
| A | GLU368 |
| A | HOH466 |
| B | GLU368 |
| B | HOH414 |
| B | HOH435 |
| B | HOH440 |
Functional Information from PROSITE/UniProt
| site_id | PS00455 |
| Number of Residues | 12 |
| Details | AMP_BINDING Putative AMP-binding domain signature. MPTSSGSEGnVK |
| Chain | Residue | Details |
| A | MET123-LYS134 | |
| site_id | PS01121 |
| Number of Residues | 15 |
| Details | CASPASE_HIS Caspase family histidine active site. HktsdStfLvFMSHG |
| Chain | Residue | Details |
| A | HIS224-GLY238 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"1574116","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"1574116","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32051255","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"30065070","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 718 |
| Chain | Residue | Details |
| A | HIS237 | proton acceptor, proton donor |
| A | GLY238 | electrostatic stabiliser |
| A | ALA285 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | ARG286 | electrostatic stabiliser |
| A | GLU390 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 718 |
| Chain | Residue | Details |
| B | HIS237 | proton acceptor, proton donor |
| B | GLY238 | electrostatic stabiliser |
| B | ALA285 | nucleofuge, nucleophile, proton acceptor, proton donor |
| B | ARG286 | electrostatic stabiliser |
| B | GLU390 | electrostatic stabiliser |
