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3DWY

Crystal Structure of the Bromodomain of Human CREBBP

Functional Information from GO Data
ChainGOidnamespacecontents
A0004402molecular_functionhistone acetyltransferase activity
A0006355biological_processregulation of DNA-templated transcription
B0004402molecular_functionhistone acetyltransferase activity
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1
ChainResidue
ALEU1109
ALEU1166
AARG1173
BLEU1109
BPRO1110

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO A 2
ChainResidue
AASP1116
APRO1117

site_idAC3
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO A 3
ChainResidue
ATRP1165
ATYR1175

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues60
DetailsBROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY
ChainResidueDetails
ASER1108-TYR1167

227561

PDB entries from 2024-11-20

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