3DWC
Trypanosoma Cruzi Metallocarboxypeptidase 1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004180 | molecular_function | carboxypeptidase activity |
| A | 0004181 | molecular_function | metallocarboxypeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0046914 | molecular_function | transition metal ion binding |
| B | 0004180 | molecular_function | carboxypeptidase activity |
| B | 0004181 | molecular_function | metallocarboxypeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0046914 | molecular_function | transition metal ion binding |
| C | 0004180 | molecular_function | carboxypeptidase activity |
| C | 0004181 | molecular_function | metallocarboxypeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0008237 | molecular_function | metallopeptidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0046914 | molecular_function | transition metal ion binding |
| D | 0004180 | molecular_function | carboxypeptidase activity |
| D | 0004181 | molecular_function | metallocarboxypeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008233 | molecular_function | peptidase activity |
| D | 0008237 | molecular_function | metallopeptidase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0046914 | molecular_function | transition metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CO A 999 |
| Chain | Residue |
| A | HIS265 |
| A | HIS269 |
| A | GLU296 |
| A | HOH1761 |
| A | HOH1762 |
| A | HOH2119 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 604 |
| Chain | Residue |
| A | GLN340 |
| A | ARG497 |
| A | HOH1235 |
| A | HOH1849 |
| A | SER309 |
| A | GLY310 |
| A | LYS336 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 609 |
| Chain | Residue |
| A | ARG348 |
| A | ILE349 |
| A | HIS409 |
| A | TYR421 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 610 |
| Chain | Residue |
| A | SER433 |
| A | HIS489 |
| A | ARG492 |
| A | ARG496 |
| A | HOH1875 |
| B | GLY440 |
| B | GLU441 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CO C 999 |
| Chain | Residue |
| C | HIS265 |
| C | HIS269 |
| C | GLU296 |
| C | HOH1765 |
| C | HOH1766 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 603 |
| Chain | Residue |
| C | SER309 |
| C | GLY310 |
| C | GLN340 |
| C | ARG497 |
| C | HOH1161 |
| C | HOH1226 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 605 |
| Chain | Residue |
| C | VAL207 |
| C | SER208 |
| C | HOH1969 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 613 |
| Chain | Residue |
| C | ASN486 |
| C | GLU488 |
| C | ARG492 |
| C | HOH1661 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CO D 999 |
| Chain | Residue |
| D | HIS265 |
| D | HIS269 |
| D | GLU296 |
| D | HOH1767 |
| D | HOH1768 |
| D | HOH2120 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 601 |
| Chain | Residue |
| D | PRO206 |
| D | VAL207 |
| D | SER208 |
| D | HOH1147 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 608 |
| Chain | Residue |
| D | SER309 |
| D | GLY310 |
| D | LYS336 |
| D | GLN340 |
| D | ARG497 |
| D | HOH1336 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CO B 999 |
| Chain | Residue |
| B | HIS265 |
| B | HIS269 |
| B | GLU296 |
| B | SER299 |
| B | HOH1763 |
| B | HOH1764 |
| B | HOH2066 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 602 |
| Chain | Residue |
| B | ARG449 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 606 |
| Chain | Residue |
| B | ARG478 |
| B | GLU483 |
| B | THR484 |
| B | HOH1935 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 607 |
| Chain | Residue |
| B | ARG79 |
| B | HOH1521 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 611 |
| Chain | Residue |
| B | GLU196 |
| B | THR197 |
| B | ARG337 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 612 |
| Chain | Residue |
| A | GOL708 |
| B | ASN486 |
| B | GLU488 |
| B | ARG492 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GLY B 701 |
| Chain | Residue |
| B | LYS222 |
| B | ASP452 |
| B | LEU453 |
| B | GLY454 |
| B | ALA702 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ALA B 702 |
| Chain | Residue |
| B | GLY454 |
| B | LYS455 |
| B | GLY701 |
| B | HOH1919 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 703 |
| Chain | Residue |
| A | GLU75 |
| A | LYS76 |
| A | ARG79 |
| A | HOH1652 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 704 |
| Chain | Residue |
| A | ARG16 |
| A | GLU243 |
| A | GLU282 |
| A | HOH2048 |
| B | ALA39 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 705 |
| Chain | Residue |
| A | GLN78 |
| A | GLY280 |
| A | PHE281 |
| C | GLU438 |
| A | LYS5 |
| A | GLU8 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 708 |
| Chain | Residue |
| A | LYS463 |
| A | GLN479 |
| A | ALA480 |
| A | GLY482 |
| A | HOH1190 |
| B | SO4612 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 710 |
| Chain | Residue |
| A | MET32 |
| A | SER37 |
| A | HOH1752 |
| site_id | CC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 711 |
| Chain | Residue |
| A | GLU441 |
| A | GLU442 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 706 |
| Chain | Residue |
| A | ALA39 |
| B | ARG16 |
| B | GLU243 |
| B | HOH2065 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 707 |
| Chain | Residue |
| B | SER333 |
| B | ARG337 |
| B | HOH1378 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 709 |
| Chain | Residue |
| B | LYS242 |
| B | GLU273 |
| B | GLN274 |
| B | CYS276 |
| B | HOH1326 |
| B | HOH1914 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1i1i |
| Chain | Residue | Details |
| A | TYR421 | |
| A | GLU296 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1i1i |
| Chain | Residue | Details |
| B | TYR421 | |
| B | GLU296 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1i1i |
| Chain | Residue | Details |
| C | TYR421 | |
| C | GLU296 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1i1i |
| Chain | Residue | Details |
| D | TYR421 | |
| D | GLU296 |
