Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. IMAHEMGHNL |
| Chain | Residue | Details |
| A | ILE142-LEU151 | |
| site_id | PS00427 |
| Number of Residues | 20 |
| Details | DISINTEGRIN_1 Disintegrins signature. CghGdCCe.QCkFsksgteCR |
| Chain | Residue | Details |
| A | CYS253-ARG272 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU146 | |
| B | GLU146 | |
| Chain | Residue | Details |
| A | GLU12 | |
| A | ASP96 | |
| A | ASN203 | |
| A | VAL215 | |
| A | ASN218 | |
| A | LEU220 | |
| A | GLU222 | |
| A | GLU225 | |
| A | ASP228 | |
| A | ASP279 | |
| A | PRO280 | |
| A | GLU282 | |
| A | ASP294 | |
| A | VAL295 | |
| B | GLU12 | |
| B | ASP96 | |
| B | HIS145 | |
| B | HIS149 | |
| B | HIS155 | |
| B | CYS200 | |
| B | ASN203 | |
| B | VAL215 | |
| B | ASN218 | |
| B | LEU220 | |
| B | GLU222 | |
| B | GLU225 | |
| B | ASP228 | |
| B | ASP279 | |
| B | PRO280 | |
| B | GLU282 | |
| B | ASP294 | |
| B | VAL295 | |
| A | HIS145 | |
| A | HIS149 | |
| A | HIS155 | |
| A | CYS200 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Necessary, but not sufficient, for proteolytic processing => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS189 | |
| B | CYS189 | |
| Chain | Residue | Details |
| A | GLN3 | |
| B | GLN3 | |
| Chain | Residue | Details |
| A | ASN183 | |
| B | ASN183 | |
